PDB entry 4x6f

View 4x6f on RCSB PDB site
Description: CD1a binary complex with sphingomyelin
Class: immune system
Keywords: CD1a, Immune complex, Lipid antigen, TCR
Deposited on 2014-12-08, released 2015-02-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-03-04, with a file datestamp of 2015-02-27.
Experiment type: XRAY
Resolution: 1.91 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: T-cell surface glycoprotein CD1a
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06126 (Start-274)
      • natural variant (9)
      • natural variant (47)
      • expression tag (275-278)
    Domains in SCOPe 2.07: d4x6fa1, d4x6fa2, d4x6fa3
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4x6fb_
  • Heterogens: 3XU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4x6fA (A:)
    lkeplsfhviwiasfynhswkqnlvsgwlsdlqthtwdsnsstivflwpwsrgnfsneew
    keletlfrirtirsfegirryahelqfeypfeiqvtggcelhsgkvsgsflqlayqgsdf
    vsfqnnswlpypvagnmakhfckvlnqnqhendithnllsdtcprfilglldagkahlqr
    qvkpeawlshgpspgpghlqlvchvsgfypkpvwvmwmrgeqeqqgtqrgdilpsadgtw
    ylratlevaageaadlscrvkhsslegqdivlywegslvpr
    

    Sequence, based on observed residues (ATOM records): (download)
    >4x6fA (A:)
    sfhviwiasfykqnlvsgwlsdlqthtwdsnsstivflwpwsrgnfsneewkeletlfri
    rtirsfegirryahelqfeypfeiqvtggcegsflqlayqgsdfvsfqnnswlpypvagn
    makhfckvlnqnqhendithnllsdtcprfilglldagkahlqrqvkpeawlshgpspgp
    ghlqlvchvsgfypkpvwvmwmrgeqeqqgtqrgdilpsadgtwylratlevaageaadl
    scrvkhsslegqdivlywegslv
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4x6fB (B:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdmgslvpr
    

    Sequence, based on observed residues (ATOM records): (download)
    >4x6fB (B:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrd