PDB entry 4x6d

View 4x6d on RCSB PDB site
Description: Immune complex
Class: immune system
Keywords: CD1a, TCR, Immune complex, Lipid antigen, IMMUNE SYSTEM
Deposited on 2014-12-08, released 2015-01-28
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-02-25, with a file datestamp of 2015-02-20.
Experiment type: XRAY
Resolution: 2.98 Å
R-factor: 0.18
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: T-cell surface glycoprotein CD1a
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06126 (Start-274)
      • variant (9)
      • variant (47)
    Domains in SCOPe 2.05: d4x6da1, d4x6da2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4x6db_
  • Chain 'C':
    Compound: T-cell surface glycoprotein CD1a
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06126
      • variant (9)
      • variant (47)
    Domains in SCOPe 2.05: d4x6dc1
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4x6dd_
  • Chain 'E':
    Compound: tcr alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4X6D
    Domains in SCOPe 2.05: d4x6de1, d4x6de2
  • Chain 'F':
    Compound: tcr beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4X6D
    Domains in SCOPe 2.05: d4x6df1, d4x6df2
  • Chain 'G':
    Compound: tcr alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4X6D
    Domains in SCOPe 2.05: d4x6dg1, d4x6dg2
  • Chain 'H':
    Compound: tcr beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4X6D
    Domains in SCOPe 2.05: d4x6dh1, d4x6dh2
  • Heterogens: OLA, PAM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4x6dA (A:)
lkeplsfhviwiasfynhswkqnlvsgwlsdlqthtwdsnsstivflwpwsrgnfsneew
keletlfrirtirsfegirryahelqfeypfeiqvtggcelhsgkvsgsflqlayqgsdf
vsfqnnswlpypvagnmakhfckvlnqnqhendithnllsdtcprfilglldagkahlqr
qvkpeawlshgpspgpghlqlvchvsgfypkpvwvmwmrgeqeqqgtqrgdilpsadgtw
ylratlevaageaadlscrvkhsslegqdivlywe

    Sequence, based on observed residues (ATOM records): (download) 
    >4x6dA (A:)
plsfhviwiasfkqnlvsgwlsdlqthtwdsnsstivflwpwsrgnfsneewkeletlfr
irtirsfegirryahelqfeypfeiqvtggcelhsgkvsgsflqlayqgsdfvsfqnnsw
lpypvagnmakhfckvlnqnqhendithnllsdtcprfilglldagkahlqrqvkpeawl
shgpspgpghlqlvchvsgfypkpvwvmwmrgeqeqqgtqrgdilpsadgtwylratlev
aageaadlscrvkhsslegqdivlywe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4x6dB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >4x6dB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdkvehsdlsfskdwsfyllyyte
ftptekdeyacrvnhvtlsqpkivkw

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4x6dC (C:)
lkeplsfhviwiasfynhswkqnlvsgwlsdlqthtwdsnsstivflwpwsrgnfsneew
keletlfrirtirsfegirryahelqfeypfeiqvtggcelhsgkvsgsflqlayqgsdf
vsfqnnswlpypvagnmakhfckvlnqnqhendithnllsdtcprfilglldagkahlqr
qvkpeawlshgpspgpghlqlvchvsgfypkpvwvmwmrgeqeqqgtqrgdilpsadgtw
ylratlevaageaadlscrvkhsslegqdivlywe

    Sequence, based on observed residues (ATOM records): (download) 
    >4x6dC (C:)
plsfhviwiasfynhswkqnlvsgwlsdlqthtwdsnsstivflwpwsrgnfsneewkel
etlfrirtirsfegirryahelqfeypfeiqvtggcelhsgkvsgsflqlayqgsdfvsf
qnnswlpypvagnmakhfckvlnqnqhendithnllsdtcprfilglldagkahlqrqvk
plshchvsgfypkpvwvqrgdilpsadgtwylratssl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4x6dD (D:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >4x6dD (D:)
iqrtpkiqvysflncyvsgfhpsdievdllkngeriekvehsdlsfskdwsfyllyytey
acrvnhvtlsqpkivkwd

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4x6dE (E:)
qkeveqdpgplsvpegaivslnctysnsafqyfmwyrqysrkgpellmytyssgnkedgr
ftaqvdksskyislfirdsqpsdsatylcamstslpnagkstfgdgttltvkpniqnpdp
avyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsn
ksdfacanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >4x6dE (E:)
eveqdpgplsvpegaivslnctysnsafqyfmwyrqysrkgpellmytyssgnkedgrft
aqvdksskyislfirdsqpsdsatylcamstslpnagkstfgdgttltvkpniqnpdpav
yqlrdsvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsacanafnns
iipedtffp

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4x6dF (F:)
nagvtqtpkfrvlktgqsmtllcaqdmnheymywyrqdpgmglrlihysvgegttakgev
pdgynvsrlkkqnfllglesaapsqtsvyfcasryflptqgmgaffgqgtrltvvedlnk
vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
wgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >4x6dF (F:)
gvtqtpkfrvlktgqsmtllcaqdmnheymywyrqdpgmglrlihysvgegttakgevpd
gynvsrlkkqnfllglesaapsqtsvyfcasryflptqgmgaffgqgtrltvvedlnkvf
ppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqp
alndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg
r

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4x6dG (G:)
qkeveqdpgplsvpegaivslnctysnsafqyfmwyrqysrkgpellmytyssgnkedgr
ftaqvdksskyislfirdsqpsdsatylcamstslpnagkstfgdgttltvkpniqnpdp
avyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsn
ksdfacanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >4x6dG (G:)
eveqdpgplsvpegaivslnctysnsafqyfmwyrqysrkgpellmytyssgnkedgrft
aqvdksskyislfirdsqpsdsatylcamstslpnagkstfgdgttltvkpniqnpdpav
yqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnks
dfacanafnnsiipedtffp

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4x6dH (H:)
nagvtqtpkfrvlktgqsmtllcaqdmnheymywyrqdpgmglrlihysvgegttakgev
pdgynvsrlkkqnfllglesaapsqtsvyfcasryflptqgmgaffgqgtrltvvedlnk
vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
wgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >4x6dH (H:)
gvtqtpkfrvlktgqsmtllcaqdmnheymywyrqdpgmglrlihysvgegttakgevpd
gynvsrlkkqnfllglesaapsqtsvyfcasryflptqgmgaffgqgtrltvvedlnkvf
ppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqp
alndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg
ra