PDB entry 4wwk

View 4wwk on RCSB PDB site
Description: Crystal structure of human TCR Alpha Chain-TRAV12-3, Beta Chain-TRBV6-5, Antigen-presenting molecule CD1d, and Beta-2-microglobulin
Class: immune system
Keywords: Innate Immunity, NKT, IMMUNE SYSTEM
Deposited on 2014-11-11, released 2016-02-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: TCR Alpha Chain-TRAV12-3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4WWK
    Domains in SCOPe 2.08: d4wwka1, d4wwka2
  • Chain 'B':
    Compound: TCR Beta Chain-TRBV6-5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4WWK (Start-242)
    Domains in SCOPe 2.08: d4wwkb1, d4wwkb2
  • Chain 'C':
    Compound: Antigen-presenting glycoprotein CD1d
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1D
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4wwkc1, d4wwkc2
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4wwkd_
  • Heterogens: NAG, JLS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4wwkA (A:)
mqkeveqdpgplsvpegaivslnctysnsafqyfmwyrqysrkgpellmytyssgnkedg
rftaqvdksskyislfirdsqpsdsatylcamsgdlntnagkstfgdgttltvkpniqnp
dpavyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavaw
snksdfacanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >4wwkA (A:)
eqdpgplsvpegaivslnctysnsafqyfmwyrqysrkgpellmytyssgnkedgrftaq
vdksskyislfirdsqpsdsatylcamsgdlntnagkstfgdgttltvkpniqnpdpavy
qlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksd
facanafn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4wwkB (B:)
mnagvtqtpkfqvlktgqsmtlqcaqdmnheymswyrqdpgmglrlihysvgagitdqge
vpngynvsrsttedfplrllsaapsqtsvyfcassqgpfqpqhfgdgtrlsiledlknvf
ppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqp
alndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg
rad

    Sequence, based on observed residues (ATOM records): (download) 
    >4wwkB (B:)
gvtqtpkfqvlktgqsmtlqcaqdmnheymswyrqdpgmglrlihysvgagitdqgevpn
gynvsrsttedfplrllsaapsqtsvyfcassqgpfqpqhfgdgtrlsiledlknvfppe
vavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpaln
dsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgrad

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4wwkC (C:)
spgvpqrlfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfs
dqqwetlqhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafq
gkdilsfqgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgks
elkkqvkpkawlsrgpspgpgrlllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpna
detwylratldvvageaaglscrvkhsslegqdivlyw

    Sequence, based on observed residues (ATOM records): (download) 
    >4wwkC (C:)
fplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfsdqqwetlq
hifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafqgkdilsfq
gtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgkselkkqvkp
kawlsrgpspgpgrlllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpnadetwylra
tldvvageaaglscrvkhsslegqdivlyw

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4wwkD (D:)
msrsvalavlallslsgleaiqrtpkiqvysrhpaengksnflncyvsgfhpsdievdll
kngeriekvehsdlsfskdwsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >4wwkD (D:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm