PDB entry 4wr5

View 4wr5 on RCSB PDB site
Description: Crystal Structure of GST Mutated with Halogenated Tyrosine (7cGST-1)
Class: transferase
Keywords: themostabilized structure, homodimeric, two domains, alfa/beta, alfa, detoxification, xenobiotic compounds, gutathione, 7 specfic sites, cytoplasmic, transferase
Deposited on 2014-10-23, released 2015-08-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-02-05, with a file datestamp of 2020-01-31.
Experiment type: XRAY
Resolution: 1.93 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutathione S-transferase class-mu 26 kDa isozyme
    Species: Schistosoma japonicum [TaxId:6182]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08515 (25-End)
      • expression tag (23-24)
    Domains in SCOPe 2.08: d4wr5a1, d4wr5a2, d4wr5a3
  • Heterogens: GSH, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4wr5A (A:)
    masmtggqqmgrdpgansgvtknsxspilgywkikglvqptrlllexleekyeehlxerd
    egdkwrnkkfelglefpnlpyxidgdvkltqsmaiirxiadkhnmlggcpkeraeismle
    gavldirygvsriayskdfetlkvdflsklpemlkmfedrlchktxlngdhvthpdfmly
    daldvvlxmdpmcldafpklvcfkkrieaipqidkylksskyiawplqgwqatfgggdhp
    pksd
    

    Sequence, based on observed residues (ATOM records): (download)
    >4wr5A (A:)
    sxspilgywkikglvqptrlllexleekyeehlxerdegdkwrnkkfelglefpnlpyxi
    dgdvkltqsmaiirxiadkhnmlggcpkeraeismlegavldirygvsriayskdfetlk
    vdflsklpemlkmfedrlchktxlngdhvthpdfmlydaldvvlxmdpmcldafpklvcf
    kkrieaipqidkylksskyiawplqgwqatfgggdhpp