PDB entry 4wo4

View 4wo4 on RCSB PDB site
Description: The molecular bases of Delta/Alpha beta T cell-mediated antigen recognition.
Class: immune system
Keywords: Immunity, IMMUNE SYSTEM
Deposited on 2014-10-15, released 2014-11-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-12-24, with a file datestamp of 2014-12-19.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.196
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Antigen-presenting glycoprotein CD1d
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1D
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15813 (Start-271)
      • expression tag (272-273)
    Domains in SCOPe 2.06: d4wo4a1, d4wo4a2, d4wo4a3
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4wo4b_
  • Chain 'C':
    Compound: TCR variable DELTA 1 CHAIN and TCR constant Alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4WO4
    Domains in SCOPe 2.06: d4wo4c1, d4wo4c2
  • Chain 'D':
    Compound: TCR variable BETA 2 (TRVB20) chain and TCR constant BETA
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4WO4
    Domains in SCOPe 2.06: d4wo4d1, d4wo4d2
  • Heterogens: JLS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4wo4A (A:)
rlfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfsdqqwet
lqhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafqgkdils
fqgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgkselkkqv
kpkawlsrgpspgpgrlllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpnadetwyl
ratldvvageaaglscrvkhsslegqdivlywpr

    Sequence, based on observed residues (ATOM records): (download) 
    >4wo4A (A:)
lfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfsdqqwetl
qhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafqgkdilsf
qgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgkselkkqvk
pkawlsrgpspgpgrlllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpnadetwylr
atldvvageaaglscrvkhsslegqdivlywpr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4wo4B (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >4wo4B (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4wo4C (C:)
hmaqkvtqaqssvsmpvrkavtlnclyetswwsyyifwykqlpskemiflirqgsdeqna
ksgrysvnfkkaaksvaltisalqledsakyfcalgvtgkltfgqgtiltvhpniqnpdp
avyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsn
ksdfacanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >4wo4C (C:)
qkvtqaqssvsmpvrkavtlnclyetswwsyyifwykqlpskemiflirqgsdeqnaksg
rysvnfkkaaksvaltisalqledsakyfcalgvtgkltfgqgtiltvhpniqnpdpavy
qlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksd
facanafnnsiipedtffps

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4wo4D (D:)
hmgavvsqhpsrvisksgtsvkiecrsldfqattmfwyrqfpkqslmlmatsnegskaty
eqgvekdkflinhasltlstltvtsahpedssfyicsapggvgaffgqgtrltvvedlkn
vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
wgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >4wo4D (D:)
gavvsqhpsrvisksgtsvkiecrsldfqattmfwyrqfpkqslmlmatsnegskatyeq
gvekdkflinhasltlstltvtsahpedssfyicsapggvgaffgqgtrltvvedlknvf
ppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqp
alndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg
ra