PDB entry 4wkn

View 4wkn on RCSB PDB site
Description: Crystal structure of Helicobacter pylori 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with methylthio-DADMe-Immucillin-A
Class: hydrolase/hydrolase inhibitor
Keywords: hydrolase, hydrolase-hydrolase inhibitor complex
Deposited on 2014-10-02, released 2015-11-25
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-12-02, with a file datestamp of 2015-11-27.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aminodeoxyfutalosine nucleosidase
    Species: Helicobacter pylori [TaxId:85963]
    Gene: mtnN, mtn, jhp_0082
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9ZMY2 (16-244)
      • expression tag (15)
    Domains in SCOPe 2.06: d4wkna1, d4wkna2
  • Heterogens: TDI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4wknA (A:)
mghhhhhhenlyfqgvqkigilgamreeitpilelfgvdfeeiplggnvfhkgvyhnkei
ivayskigkvhstltttsmilafgvqkvlfsgvagslvkdlkindllvatqlvqhdvdls
afdhplgfipesaifietsgslnalakkianeqhialkegviasgdqfvhskerkeflvs
efkasavemegasvafvcqkfgvpccvlrsisdnadekagmsfdefleksahtsakflks
mvdel

    Sequence, based on observed residues (ATOM records): (download) 
    >4wknA (A:)
vqkigilgamreeitpilelfgvdfeeiplggnvfhkgvyhnkeiivayskigkvhstlt
ttsmilafgvqkvlfsgvagslvkdlkindllvatqlvqhdvdlsafdhplgfipesaif
ietsgslnalakkianeqhialkegviasgdqfvhskerkeflvsefkasavemegasva
fvcqkfgvpccvlrsisdnadekagmsfdefleksahtsakflksmvdel