PDB entry 4uyh

View 4uyh on RCSB PDB site
Description: N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 1-((2R,4S)-2-methyl-4-(phenylamino)-6-(4-(piperidin-1-ylmethyl)phenyl)-3,4-dihydroquinolin-1(2H)-yl)ethanone
Class: transcription
Keywords: transcription, histone, epigenetic reader, bet, brd2, bromodomain
Deposited on 2014-08-31, released 2014-10-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-10-22, with a file datestamp of 2014-10-17.
Experiment type: XRAY
Resolution: 1.73 Å
R-factor: 0.17263
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4uyha_
  • Chain 'B':
    Compound: Bromodomain-containing protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4uyhb_
  • Chain 'C':
    Compound: Bromodomain-containing protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4uyhc_
  • Heterogens: 9S3, SO4, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4uyhA (A:)
gsshhhhhhssglvprgshmsnpkkpgrvtnqlqylhkvvmkalwkhqfawpfrqpvdav
klglpdyhkiikqpmdmgtikrrlennyywaasecmqdfntmftncyiynkptddivlma
qtlekiflqkvasmpqeeqelvvtipknshkkga

    Sequence, based on observed residues (ATOM records): (download) 
    >4uyhA (A:)
vtnqlqylhkvvmkalwkhqfawpfrqpvdavklglpdyhkiikqpmdmgtikrrlenny
ywaasecmqdfntmftncyiynkptddivlmaqtlekiflqkvasmpqe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4uyhB (B:)
gsshhhhhhssglvprgshmsnpkkpgrvtnqlqylhkvvmkalwkhqfawpfrqpvdav
klglpdyhkiikqpmdmgtikrrlennyywaasecmqdfntmftncyiynkptddivlma
qtlekiflqkvasmpqeeqelvvtipknshkkga

    Sequence, based on observed residues (ATOM records): (download) 
    >4uyhB (B:)
tnqlqylhkvvmkalwkhqfawpfrqpvdavklglpdyhkiikqpmdmgtikrrlennyy
waasecmqdfntmftncyiynkptddivlmaqtlekiflqkvasmpq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4uyhC (C:)
gsshhhhhhssglvprgshmsnpkkpgrvtnqlqylhkvvmkalwkhqfawpfrqpvdav
klglpdyhkiikqpmdmgtikrrlennyywaasecmqdfntmftncyiynkptddivlma
qtlekiflqkvasmpqeeqelvvtipknshkkga

    Sequence, based on observed residues (ATOM records): (download) 
    >4uyhC (C:)
nqlqylhkvvmkalwkhqfawpfrqpvdavklglpdyhkiikqpmdmgtikrrlennyyw
aasecmqdfntmftncyiynkptddivlmaqtlekiflqkvasmp