PDB entry 4uye

View 4uye on RCSB PDB site
Description: BROMODOMAIN OF HUMAN BRPF1 WITH N-1,3-dimethyl-2-oxo-6-(piperidin-1- yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl-2-methoxybenzamide
Class: transcription
Keywords: transcription, inhibitor, histone, epigenetic reader, antagonist
Deposited on 2014-08-30, released 2014-09-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-12-03, with a file datestamp of 2014-11-28.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: 0.17693
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peregrin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4uyea_
  • Chain 'B':
    Compound: Peregrin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4uyeb_
  • Heterogens: EDO, 9F9, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4uyeA (A:)
gqqiamemqltpflillrktleqlqekdtgnifsepvplsevpdyldhikkpmdfftmkq
nleayrylnfddfeedfnlivsnclkynakdtifyraavrlreqggavlrqarrqaek

    Sequence, based on observed residues (ATOM records): (download) 
    >4uyeA (A:)
qltpflillrktleqlqekdtgnifsepvplsevpdyldhikkpmdfftmkqnleayryl
nfddfeedfnlivsnclkynakdtifyraavrlreqggavlrqarrqae

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4uyeB (B:)
gqqiamemqltpflillrktleqlqekdtgnifsepvplsevpdyldhikkpmdfftmkq
nleayrylnfddfeedfnlivsnclkynakdtifyraavrlreqggavlrqarrqaek

    Sequence, based on observed residues (ATOM records): (download) 
    >4uyeB (B:)
qltpflillrktleqlqekdtgnifsepvplsevpdyldhikkpmdfftmkqnleayryl
nfddfeedfnlivsnclkynakdtifyraavrlreqggavlrqarrqae