PDB entry 4urx

View 4urx on RCSB PDB site
Description: The crystal structure of H-Ras and SOS in complex with ligands
Class: signaling protein
Keywords: signaling protein
Deposited on 2014-07-02, released 2015-03-04
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-03-25, with a file datestamp of 2015-03-20.
Experiment type: XRAY
Resolution: 2.49 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'R':
    Compound: gtpase hras
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01112 (19-184)
      • expression tag (18)
    Domains in SCOPe 2.06: d4urxr1, d4urxr2
  • Chain 'S':
    Compound: Son of sevenless homolog 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4urxs_
  • Heterogens: FK1, HXY, FMT, HOH

PDB Chain Sequences:

  • Chain 'R':
    Sequence, based on SEQRES records: (download)
    >4urxR (R:)
    mhhhhhhgggenlyfqgshmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyr
    kqvvidgetclldildtagqeeysamrdqymrtgegflcvfainntksfedihqyreqik
    rvkdsddvpmvlvgnkcdlaartvesrqaqdlarsygipyietsaktrqgvedafytlvr
    eirqh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4urxR (R:)
    hmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildta
    gqeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcd
    laartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh
    

  • Chain 'S':
    Sequence, based on SEQRES records: (download)
    >4urxS (S:)
    meeqmrlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpn
    fvrtflttyrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyi
    qpvqlrvlnvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkki
    ardngpghnitfqsspptvewhisrpghietfdlltlhpieiarqltllesdlyravqps
    elvgsvwtkedkeinspnllkmirhttnltlwfekcivetenleervavvsriieilqvf
    qelnnfngvlevvsamnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsi
    nppcvpffgiyltnilkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclr
    vesdikrffenlnpmgnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrp
    snprpgt
    

    Sequence, based on observed residues (ATOM records): (download)
    >4urxS (S:)
    qmrlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpnfvr
    tflttyrsfckpqellsliierfeipepelsaelkrfrkeyiqpvqlrvlnvcrhwvehh
    fydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiasspptvewhisrpghie
    tfdlltlhpieiarqltllesdlyravqpselvgsvwtkedkeinspnllkmirhttnlt
    lwfekcivetenleervavvsriieilqvfqelnnfngvlevvsamnsspvyrldhtfeq
    ipsrqkkileeahelsedhykkylaklrsinppcvpffgiyltnilkteegnpevlkrhg
    kelinfskrrkvaeitgeiqqyqnqpyclrvesdikrffenlnpmgnsmekeftdylfnk
    sleieprnpkplprfpkkysyplkspgvrpsnp