PDB entry 4ui1

View 4ui1 on RCSB PDB site
Description: Crystal structure of the human RGMC-BMP2 complex
Class: signaling protein
Keywords: signaling protein, bone morphogenetic protein pathway, hemojuvelin, morphogen, axon guidance, cell surface receptor signaling
Deposited on 2015-03-27, released 2015-05-06
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-05-06, with a file datestamp of 2015-05-01.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bone morphogenetic protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4ui1a_
  • Chain 'B':
    Compound: Bone morphogenetic protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4ui1b_
  • Chain 'C':
    Compound: hemojuvelin
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: hemojuvelin
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NO3, CL, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4ui1A (A:)
    qakhkqrkrlkssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnh
    aivqtlvnsvnskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr
    

    Sequence, based on observed residues (ATOM records): (download)
    >4ui1A (A:)
    kssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvnsv
    nskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4ui1B (B:)
    qakhkqrkrlkssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnh
    aivqtlvnsvnskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr
    

    Sequence, based on observed residues (ATOM records): (download)
    >4ui1B (B:)
    lkssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvns
    vnskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.