PDB entry 4uec

View 4uec on RCSB PDB site
Description: Complex of D. melanogaster eIF4E with eIF4G and cap analog
Class: translation
Keywords: translation, gene regulation, cap binding protein, 4e binding protein, translation initiation
Deposited on 2014-12-16, released 2015-02-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-04-15, with a file datestamp of 2015-04-10.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: eukaryotic translation initiation factor 4e
    Species: Drosophila melanogaster [TaxId:7227]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P48598 (4-End)
      • expression tag (1-3)
    Domains in SCOPe 2.08: d4ueca1, d4ueca2
  • Chain 'B':
    Compound: eukaryotic translation initiation factor 4g, isoform a
    Species: Drosophila melanogaster [TaxId:7227]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: eukaryotic translation initiation factor 4e
    Species: Drosophila melanogaster [TaxId:7227]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P48598 (4-End)
      • expression tag (1-3)
    Domains in SCOPe 2.08: d4uecc1, d4uecc2
  • Heterogens: MGT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4uecA (A:)
gphmkhplmnvwtlwylendrskswedmqneitsfdtvedfwslynhikppseiklgsdy
slfkknirpmwedaankqggrwvitlnkssktdldnlwldvllcligeafdhsdqicgav
inirgksnkisiwtadgnneeaaleighklrdalrlgrnnslqyqlhkdtmvkqgsnvks
iytl

    Sequence, based on observed residues (ATOM records): (download) 
    >4uecA (A:)
phmkhplmnvwtlwylendrskswedmqneitsfdtvedfwslynhikppseiklgsdys
lfkknirpmwedaankqggrwvitlnkssktdldnlwldvllcligeafdhsdqicgavi
nirgksnkisiwtadgnneeaaleighklrdalrlgrnnslqyqlhkdtmv

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4uecC (C:)
gphmkhplmnvwtlwylendrskswedmqneitsfdtvedfwslynhikppseiklgsdy
slfkknirpmwedaankqggrwvitlnkssktdldnlwldvllcligeafdhsdqicgav
inirgksnkisiwtadgnneeaaleighklrdalrlgrnnslqyqlhkdtmvkqgsnvks
iytl

    Sequence, based on observed residues (ATOM records): (download) 
    >4uecC (C:)
phmkhplmnvwtlwylendrskswedmqneitsfdtvedfwslynhikppseiklgsdys
lfkknirpmwedaankqggrwvitlnkssktdldnlwldvllcligeafdhsdqicgavi
nirgksnkisiwtadgnneeaaleighklrdalrlgrnnslqyqlhkdtmv