PDB entry 4u1g

View 4u1g on RCSB PDB site
Description: Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to monoclonal antibody QA1
Class: immune system
Keywords: malaria erythrocyte invasion antibody-mediated inhibition, immune system
Deposited on 2014-07-15, released 2014-08-13
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-07-22, with a file datestamp of 2015-07-17.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Reticulocyte binding protein 5
    Species: Plasmodium falciparum [TaxId:5833]
    Database cross-references and differences (RAF-indexed):
    • Uniprot B2L3N7
      • engineered mutation (215)
  • Chain 'B':
    Compound: QA1 monoclonal antibody heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4U1G
  • Chain 'C':
    Compound: QA1 monoclonal antibody light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4U1G
    Domains in SCOPe 2.06: d4u1gc1, d4u1gc2
  • Chain 'D':
    Compound: Reticulocyte binding protein 5
    Species: Plasmodium falciparum [TaxId:5833]
    Database cross-references and differences (RAF-indexed):
    • Uniprot B2L3N7
      • engineered mutation (215)
  • Chain 'E':
    Compound: QA1 monoclonal antibody heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4U1G
  • Chain 'F':
    Compound: QA1 monoclonal antibody light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4U1G
    Domains in SCOPe 2.06: d4u1gf1, d4u1gf2

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4u1gC (C:)
    mvstpqflvfllfwipasrgdivltqspaslavslgqratiscrasqsvstssytyfhwy
    qqkpgqppklliryasnlesgvparfsgsgsgtdftlnihpveeedtatyycqhsweipy
    tfgggtkleikradaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserq
    ngvlnswtdqdskdstysmsstltltkdeyerhnsytceathktstspivksfnrnec
    

    Sequence, based on observed residues (ATOM records): (download)
    >4u1gC (C:)
    divltqspaslavslgqratiscrasqsvstssytyfhwyqqkpgqppklliryasnles
    gvparfsgsgsgtdftlnihpveeedtatyycqhsweipytfgggtkleikradaaptvs
    ifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysms
    stltltkdeyerhnsytceathktstspivksfnr
    

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >4u1gF (F:)
    mvstpqflvfllfwipasrgdivltqspaslavslgqratiscrasqsvstssytyfhwy
    qqkpgqppklliryasnlesgvparfsgsgsgtdftlnihpveeedtatyycqhsweipy
    tfgggtkleikradaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserq
    ngvlnswtdqdskdstysmsstltltkdeyerhnsytceathktstspivksfnrnec
    

    Sequence, based on observed residues (ATOM records): (download)
    >4u1gF (F:)
    divltqspaslavslgqratiscrasqsvstssytyfhwyqqkpgqppklliryasnles
    gvparfsgsgsgtdftlnihpveeedtatyycqhsweipytfgggtkleikradaaptvs
    ifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysms
    stltltkdeyerhnsytceathktstspivksfnr