PDB entry 4u1g
View 4u1g on RCSB PDB site
Description: Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to monoclonal antibody QA1
Class: immune system
Keywords: malaria erythrocyte invasion antibody-mediated inhibition, immune system
Deposited on
2014-07-15, released
2014-08-13
The last revision prior to the SCOPe 2.06 freeze date was dated
2015-07-22, with a file datestamp of
2015-07-17.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.11
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Reticulocyte binding protein 5
Species: Plasmodium falciparum [TaxId:5833]
Database cross-references and differences (RAF-indexed):
- Uniprot B2L3N7
- engineered mutation (215)
- Chain 'B':
Compound: QA1 monoclonal antibody heavy chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
- Chain 'C':
Compound: QA1 monoclonal antibody light chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4u1gc1, d4u1gc2 - Chain 'D':
Compound: Reticulocyte binding protein 5
Species: Plasmodium falciparum [TaxId:5833]
Database cross-references and differences (RAF-indexed):
- Uniprot B2L3N7
- engineered mutation (215)
- Chain 'E':
Compound: QA1 monoclonal antibody heavy chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
- Chain 'F':
Compound: QA1 monoclonal antibody light chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4u1gf1, d4u1gf2
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
No sequence available.
- Chain 'C':
Sequence, based on SEQRES records: (download)
>4u1gC (C:)
mvstpqflvfllfwipasrgdivltqspaslavslgqratiscrasqsvstssytyfhwy
qqkpgqppklliryasnlesgvparfsgsgsgtdftlnihpveeedtatyycqhsweipy
tfgggtkleikradaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserq
ngvlnswtdqdskdstysmsstltltkdeyerhnsytceathktstspivksfnrnec
Sequence, based on observed residues (ATOM records): (download)
>4u1gC (C:)
divltqspaslavslgqratiscrasqsvstssytyfhwyqqkpgqppklliryasnles
gvparfsgsgsgtdftlnihpveeedtatyycqhsweipytfgggtkleikradaaptvs
ifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysms
stltltkdeyerhnsytceathktstspivksfnr
- Chain 'D':
No sequence available.
- Chain 'E':
No sequence available.
- Chain 'F':
Sequence, based on SEQRES records: (download)
>4u1gF (F:)
mvstpqflvfllfwipasrgdivltqspaslavslgqratiscrasqsvstssytyfhwy
qqkpgqppklliryasnlesgvparfsgsgsgtdftlnihpveeedtatyycqhsweipy
tfgggtkleikradaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserq
ngvlnswtdqdskdstysmsstltltkdeyerhnsytceathktstspivksfnrnec
Sequence, based on observed residues (ATOM records): (download)
>4u1gF (F:)
divltqspaslavslgqratiscrasqsvstssytyfhwyqqkpgqppklliryasnles
gvparfsgsgsgtdftlnihpveeedtatyycqhsweipytfgggtkleikradaaptvs
ifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysms
stltltkdeyerhnsytceathktstspivksfnr