PDB entry 4tpi

View 4tpi on RCSB PDB site
Description: the refined 2.2-angstroms (0.22-nm) x-ray crystal structure of the ternary complex formed by bovine trypsinogen, valine-valine and the arg15 analogue of bovine pancreatic trypsin inhibitor
Class: complex (proteinase/inhibitor)
Keywords: complex (proteinase/inhibitor)
Deposited on 1985-06-11, released 1985-11-08
The last revision prior to the SCOP 1.73 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: -
Resolution: 2.2 Å
R-factor: 0.17
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'I':
    Compound: bovine pancreatic trypsin inhibitor
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00974 (0-57)
      • conflict (14)
    Domains in SCOP 1.73: d4tpii_
  • Chain 'S':
    Compound: dipeptide
  • Chain 'Z':
    Compound: trypsinogen
    Species: Bos taurus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d4tpiz_
  • Heterogens: SO4, CA, HOH

PDB Chain Sequences:

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4tpiI (I:)
rpdfcleppytgpcrariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga

  • Chain 'S':
    No sequence available.

  • Chain 'Z':
    Sequence, based on SEQRES records: (download) 
    >4tpiZ (Z:)
vddddkivggytcgantvpyqvslnsgyhfcggslinsqwvvsaahcyksgiqvrlgedn
invvegneqfisasksivhpsynsntlnndimliklksaaslnsrvasislptscasagt
qclisgwgntkssgtsypdvlkclkapilsdsscksaypgqitsnmfcagyleggkdscq
gdsggpvvcsgklqgivswgsgcaqknkpgvytkvcnyvswikqtiasn

    Sequence, based on observed residues (ATOM records): (download) 
    >4tpiZ (Z:)
ivggytcgantvpyqvslnsgyhfcggslinsqwvvsaahcyksgiqvrlgedninvveg
neqfisasksivhpsynsntlnndimliklksaaslnsrvasislptscasagtqclisg
wgntkssgtsypdvlkclkapilsdsscksaypgqitsnmfcagyleggkdscqgdsggp
vvcsgklqgivswgsgcaqknkpgvytkvcnyvswikqtiasn