PDB entry 4tl5

View 4tl5 on RCSB PDB site
Description: Crystal Structure of Human Transthyretin Ser85Pro Mutant
Class: transport protein
Keywords: human transthyretin, amyloid, transthyretin, mutant, TRANSPORT PROTEIN
Deposited on 2014-05-29, released 2015-10-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-12-09, with a file datestamp of 2015-12-04.
Experiment type: XRAY
Resolution: 1.44 Å
R-factor: N/A
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Gene: TTR, PALB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered mutation (76)
    Domains in SCOPe 2.08: d4tl5a_
  • Chain 'B':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Gene: TTR, PALB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered mutation (76)
    Domains in SCOPe 2.08: d4tl5b_
  • Heterogens: NA, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4tl5A (A:)
kcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegi
ykveidtksywkalgippfhehaevvftandsgprrytiaallspysysttavvtnpkeh
hhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4tl5A (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgippfhehaevvftandsgprrytiaallspysysttavvtnp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4tl5B (B:)
kcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegi
ykveidtksywkalgippfhehaevvftandsgprrytiaallspysysttavvtnpkeh
hhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4tl5B (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgippfhehaevvftandsgprrytiaallspysysttavvtn