PDB entry 4s35

View 4s35 on RCSB PDB site
Description: AMPPCP and TMP bound Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5
Class: transferase
Keywords: Transferase, ATP binding, TMP binding
Deposited on 2015-01-26, released 2016-01-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-06-28, with a file datestamp of 2017-06-23.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thymidylate kinase
    Species: Aquifex aeolicus [TaxId:224324]
    Gene: aq_969, tmk
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4s35a_
  • Chain 'B':
    Compound: thymidylate kinase
    Species: Aquifex aeolicus [TaxId:224324]
    Gene: aq_969, tmk
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4s35b_
  • Heterogens: ACP, TMP, MG, EDO, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4s35A (A:)
    mliafegidgsgkttqakklyeylkqkgyfvslyrepggtkvgevlreillteelderte
    lllfeasrsklieekiipdlkrdkvvildrfvlstiayqgygkgldvefiknlnefatrg
    vkpditllldipvdialrrlkeknrfenkeflekvrkgflelakeeenvvvidasgeeee
    vfkeilralsgvlrv
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4s35B (B:)
    mliafegidgsgkttqakklyeylkqkgyfvslyrepggtkvgevlreillteelderte
    lllfeasrsklieekiipdlkrdkvvildrfvlstiayqgygkgldvefiknlnefatrg
    vkpditllldipvdialrrlkeknrfenkeflekvrkgflelakeeenvvvidasgeeee
    vfkeilralsgvlrv
    

    Sequence, based on observed residues (ATOM records): (download)
    >4s35B (B:)
    mliafegidgsgkttqakklyeylkqkgyfvslyrepggtkvgevlreillteelderte
    lllfeasrsklieekiipdlkrdkvvildrfvlstiayqgygkgldvefiknlnefatrg
    vkpditllldipvdialrrlkeknrfenkeflekvrkgflelakeeenvvvidasgeeee
    vfkeilralsgvlr