PDB entry 4s2n

View 4s2n on RCSB PDB site
Description: OXA-48 in complex with Avibactam at pH 8.5
Class: hydrolase/antibiotic
Keywords: hydrolase-antibiotic complex
Deposited on 2015-01-21, released 2015-02-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: bla OXA-48, blaOXA-48, FP68_27275, KPE71T_00045
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4s2na_
  • Chain 'B':
    Compound: Beta-lactamase
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: bla OXA-48, blaOXA-48, FP68_27275, KPE71T_00045
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4s2nb_
  • Chain 'C':
    Compound: Beta-lactamase
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: bla OXA-48, blaOXA-48, FP68_27275, KPE71T_00045
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4s2nc_
  • Chain 'D':
    Compound: Beta-lactamase
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: bla OXA-48, blaOXA-48, FP68_27275, KPE71T_00045
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4s2nd_
  • Heterogens: NXL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4s2nA (A:)
mrvlalsavflvasiigmpavakewqenkswnahftehksqgvvvlwnenkqqgftnnlk
ranqaflpastfkipnslialdlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvv
pvyqefarqigearmskmlhafdygnedisgnvdsfwldggirisateqisflrklyhnk
lhvsersqrivkqamlteangdyiiraktgystriepkigwwvgwvelddnvwffamnmd
mptsdglglrqaitkevlkqekiip

    Sequence, based on observed residues (ATOM records): (download) 
    >4s2nA (A:)
kewqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfkipnsliald
lgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskmlhaf
dygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamlteangd
yiiraktgystriepkigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkqek
iip

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4s2nB (B:)
mrvlalsavflvasiigmpavakewqenkswnahftehksqgvvvlwnenkqqgftnnlk
ranqaflpastfkipnslialdlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvv
pvyqefarqigearmskmlhafdygnedisgnvdsfwldggirisateqisflrklyhnk
lhvsersqrivkqamlteangdyiiraktgystriepkigwwvgwvelddnvwffamnmd
mptsdglglrqaitkevlkqekiip

    Sequence, based on observed residues (ATOM records): (download) 
    >4s2nB (B:)
ewqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfkipnslialdl
gvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskmlhafd
ygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamlteangdy
iiraktgystriepkigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkqeki
ip

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4s2nC (C:)
mrvlalsavflvasiigmpavakewqenkswnahftehksqgvvvlwnenkqqgftnnlk
ranqaflpastfkipnslialdlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvv
pvyqefarqigearmskmlhafdygnedisgnvdsfwldggirisateqisflrklyhnk
lhvsersqrivkqamlteangdyiiraktgystriepkigwwvgwvelddnvwffamnmd
mptsdglglrqaitkevlkqekiip

    Sequence, based on observed residues (ATOM records): (download) 
    >4s2nC (C:)
ewqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfkipnslialdl
gvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskmlhafd
ygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamlteangdy
iiraktgystriepkigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkqeki
ip

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4s2nD (D:)
mrvlalsavflvasiigmpavakewqenkswnahftehksqgvvvlwnenkqqgftnnlk
ranqaflpastfkipnslialdlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvv
pvyqefarqigearmskmlhafdygnedisgnvdsfwldggirisateqisflrklyhnk
lhvsersqrivkqamlteangdyiiraktgystriepkigwwvgwvelddnvwffamnmd
mptsdglglrqaitkevlkqekiip

    Sequence, based on observed residues (ATOM records): (download) 
    >4s2nD (D:)
ewqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfkipnslialdl
gvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskmlhafd
ygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamlteangdy
iiraktgystriepkigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkqeki
ip