PDB entry 4rv4

View 4rv4 on RCSB PDB site
Description: 2.65 Angstrom Resolution Crystal Structure of an orotate phosphoribosyltransferase from Bacillus anthracis str. 'Ames Ancestor' in complex with 5-phospho-alpha-D-ribosyl diphosphate (PRPP)
Class: transferase
Keywords: PYRIMIDINE RIBONUCLEOTIDE BIOSYNTHESIS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, GLYCOSYLTRANSFERASE, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE, NIAID, National Institute of Allergy and Infectious Diseases
Deposited on 2014-11-24, released 2014-12-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: orotate phosphoribosyltransferase
    Species: Bacillus anthracis [TaxId:1392]
    Gene: BAS3733, BA_4021, GBAA_4021, pyrE
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q81WF6 (24-233)
      • expression tag (21-23)
    Domains in SCOPe 2.08: d4rv4a1, d4rv4a2
  • Chain 'B':
    Compound: orotate phosphoribosyltransferase
    Species: Bacillus anthracis [TaxId:1392]
    Gene: BAS3733, BA_4021, GBAA_4021, pyrE
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q81WF6 (24-233)
      • expression tag (16-23)
    Domains in SCOPe 2.08: d4rv4b1, d4rv4b2
  • Chain 'C':
    Compound: orotate phosphoribosyltransferase
    Species: Bacillus anthracis [TaxId:1392]
    Gene: BAS3733, BA_4021, GBAA_4021, pyrE
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q81WF6 (24-233)
      • expression tag (20-23)
    Domains in SCOPe 2.08: d4rv4c1, d4rv4c2
  • Heterogens: PRP, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4rv4A (A:)
mhhhhhhssgvdlgtenlyfqsnamkkeiashlleigavflqpndpftwssgmkspiycd
nrltlsypkvrqtiaagleelikehfptveviagtatagiahaawvsdrmdlpmcyvrsk
akghgkgnqiegkaekgqkvvvvedlistggsaitcvealreagcevlgivsiftyelea
gkekleaanvasyslsdysaltevaaekgiigqaetkklqewrknpadeawita

    Sequence, based on observed residues (ATOM records): (download) 
    >4rv4A (A:)
snamkkeiashlleigavflqpndpftwssgmkspiycdnrltlsypkvrqtiaagleel
ikehfptveviagtatagiahaawvsdrmdlpmcyvrqiegkaekgqkvvvvedlistgg
saitcvealreagcevlgivsiftyeleagkekleaanvasyslsdysaltevaaekgii
gqaetkklqewrknpadeawita

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4rv4B (B:)
mhhhhhhssgvdlgtenlyfqsnamkkeiashlleigavflqpndpftwssgmkspiycd
nrltlsypkvrqtiaagleelikehfptveviagtatagiahaawvsdrmdlpmcyvrsk
akghgkgnqiegkaekgqkvvvvedlistggsaitcvealreagcevlgivsiftyelea
gkekleaanvasyslsdysaltevaaekgiigqaetkklqewrknpadeawita

    Sequence, based on observed residues (ATOM records): (download) 
    >4rv4B (B:)
nlyfqsnamkkeiashlleigavflqpndpftwssgmkspiycdnrltlsypkvrqtiaa
gleelikehfptveviagtatagiahaawvsdrmdlpmcyvrsgnqiegkaekgqkvvvv
edlistggsaitcvealreagcevlgivsiftyeleagkekleaanvasyslsdysalte
vaaekgiigqaetkklqewrknpadeawita

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4rv4C (C:)
mhhhhhhssgvdlgtenlyfqsnamkkeiashlleigavflqpndpftwssgmkspiycd
nrltlsypkvrqtiaagleelikehfptveviagtatagiahaawvsdrmdlpmcyvrsk
akghgkgnqiegkaekgqkvvvvedlistggsaitcvealreagcevlgivsiftyelea
gkekleaanvasyslsdysaltevaaekgiigqaetkklqewrknpadeawita

    Sequence, based on observed residues (ATOM records): (download) 
    >4rv4C (C:)
qsnamkkeiashlleigavflqpndpftwssgmkspiycdnrltlsypkvrqtiaaglee
likehfptveviagtatagiahaawvsdrmdlpmcyviegkaekgqkvvvvedlistggs
aitcvealreagcevlgivsiftyeleagkekleaanvasyslsdysaltevaaekgiig
qaetkklqewrknpadeawita