PDB entry 4ri5

View 4ri5 on RCSB PDB site
Description: Crystal structure of PTPN3 (PTPH1) D811E mutant in complex with metavanadate
Class: hydrolase
Keywords: Alpha Beta, Hydrolase
Deposited on 2014-10-05, released 2015-03-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-07-18, with a file datestamp of 2018-07-13.
Experiment type: XRAY
Resolution: 1.26 Å
R-factor: N/A
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein phosphatase non-receptor type 3
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPH1, PTPN3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26045 (24-End)
      • expression tag (21-23)
      • engineered mutation (207)
    Domains in SCOPe 2.08: d4ri5a1, d4ri5a2
  • Chain 'B':
    Compound: Tyrosine-protein phosphatase non-receptor type 3
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPH1, PTPN3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26045 (24-End)
      • expression tag (21-23)
      • engineered mutation (207)
    Domains in SCOPe 2.08: d4ri5b1, d4ri5b2
  • Heterogens: GOL, VN4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ri5A (A:)
mhhhhhhssgvdlgtenlyfqsnadtlegsmaqlkkglesgtvliqfeqlyrkkpglait
faklpqnldknrykdvlpydttrvllqgnedyinasyvnmeipaanlvnkyiatqgplph
tcaqfwqvvwdqklslivmlttltergrtkchqywpdppdvmnhggfhiqcqsedctiay
vsremlvtntqtgeehtvthlqyvawpehgvpddssdflefvnyvrslrvdsepvlvhcs
agigrtgvlvtmetamclternlpiypldivrkmrdqrammvqtssqykfvceailrvye
eglvqm

    Sequence, based on observed residues (ATOM records): (download) 
    >4ri5A (A:)
snadtlegsmaqlkkglesgtvliqfeqlyrkkpglaitfaklpqnldknrykdvlpydt
trvllqgnedyinasyvnmeipaanlvnkyiatqgplphtcaqfwqvvwdqklslivmlt
tltergrtkchqywpdppdvmnhggfhiqcqsedctiayvsremlvtntqtgeehtvthl
qyvawpehgvpddssdflefvnyvrslrvdsepvlvhcsagigrtgvlvtmetamclter
nlpiypldivrkmrdqrammvqtssqykfvceailrvyeeglvq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ri5B (B:)
mhhhhhhssgvdlgtenlyfqsnadtlegsmaqlkkglesgtvliqfeqlyrkkpglait
faklpqnldknrykdvlpydttrvllqgnedyinasyvnmeipaanlvnkyiatqgplph
tcaqfwqvvwdqklslivmlttltergrtkchqywpdppdvmnhggfhiqcqsedctiay
vsremlvtntqtgeehtvthlqyvawpehgvpddssdflefvnyvrslrvdsepvlvhcs
agigrtgvlvtmetamclternlpiypldivrkmrdqrammvqtssqykfvceailrvye
eglvqm

    Sequence, based on observed residues (ATOM records): (download) 
    >4ri5B (B:)
snadtlegsmaqlkkglesgtvliqfeqlyrkkpglaitfaklpqnldknrykdvlpydt
trvllqgnedyinasyvnmeipaanlvnkyiatqgplphtcaqfwqvvwdqklslivmlt
tltergrtkchqywpdppdvmnhggfhiqcqsedctiayvsremlvtntqtgeehtvthl
qyvawpehgvpddssdflefvnyvrslrvdsepvlvhcsagigrtgvlvtmetamclter
nlpiypldivrkmrdqrammvqtssqykfvceailrvyeeglvq