PDB entry 4rak

View 4rak on RCSB PDB site
Description: Crystal structure of nuclear receptor subfamily 1, group h, member 2 (lxrb) complexed with partial agonist
Class: transcription/agonist
Keywords: NHR, NR1H2, LXR-B, LXRB, UNR, NER-I, RIP15, NER, Ligand Binding Domain, Nuclear Hormone Receptor, RXR, TRANSCRIPTION-AGONIST complex
Deposited on 2014-09-10, released 2014-12-31
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-01-14, with a file datestamp of 2015-01-09.
Experiment type: XRAY
Resolution: 2.04 Å
R-factor: 0.232
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: oxysterols receptor lxr-beta
    Species: Homo sapiens [TaxId:9606]
    Gene: NR1H2, LXRB, NER, UNR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4raka_
  • Chain 'B':
    Compound: oxysterols receptor lxr-beta
    Species: Homo sapiens [TaxId:9606]
    Gene: NR1H2, LXRB, NER, UNR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4rakb_
  • Heterogens: BU1, 652, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4rakA (A:)
mhhhhhhgenlyfqgsegegvqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgad
pqsrdarqqrfahftelaiisvqeivdfakqvpgflqlgredqiallkastieimlleta
rrynhetecitflkdftyskddfhraglqvefinpifefsramrrlglddaeyalliain
ifsadrpnvqepgrvealqqpyveallsytrikrpqdqlrfprmlmklvslrtlssvhse
qvfalrlqdkklppllseiwdvhe

    Sequence, based on observed residues (ATOM records): (download) 
    >4rakA (A:)
vqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgadpqsrdarqqrfahftelaii
svqeivdfakqvpgflqlgredqiallkastieimlletarrynhetecitflkdftysk
ddfhraglqvefinpifefsramrrlglddaeyalliainifsadrpnvqepgrvealqq
pyveallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrklppllseiw

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4rakB (B:)
mhhhhhhgenlyfqgsegegvqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgad
pqsrdarqqrfahftelaiisvqeivdfakqvpgflqlgredqiallkastieimlleta
rrynhetecitflkdftyskddfhraglqvefinpifefsramrrlglddaeyalliain
ifsadrpnvqepgrvealqqpyveallsytrikrpqdqlrfprmlmklvslrtlssvhse
qvfalrlqdkklppllseiwdvhe

    Sequence, based on observed residues (ATOM records): (download) 
    >4rakB (B:)
qltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwpdarqqrfahftelaiisvqeivdfa
kqvpgflqlgredqiallkastieimlletarrynhetecitflkdftyskddfhraglq
vefinpifefsramrrlglddaeyalliainifsadrpnvqepgrvealqqpyveallsy
trikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwd