PDB entry 4r9h

View 4r9h on RCSB PDB site
Description: Crystal structure of dimeric S33C beta-2 microglobulin mutant at 1.9 Angstrom resolution
Class: immune system
Keywords: amyloidosis, protein aggregation, covalent dimer, oligomerization, beta sandwich, inclusion bodies, IMMUNE SYSTEM
Deposited on 2014-09-05, released 2015-09-09
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-09-09, with a file datestamp of 2015-09-04.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P, NM_004048
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • expression tag (0)
      • engineered mutation (33)
    Domains in SCOPe 2.05: d4r9ha_
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P, NM_004048
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-End)
      • engineered mutation (33)
    Domains in SCOPe 2.05: d4r9hb_
  • Chain 'C':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P, NM_004048
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-End)
      • engineered mutation (33)
    Domains in SCOPe 2.05: d4r9hc_
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P, NM_004048
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-End)
      • expression tag (0)
      • engineered mutation (33)
    Domains in SCOPe 2.05: d4r9hd_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4r9hA (A:)
miqrtpkiqvysrhpaengksnflncyvsgfhpcdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4r9hB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpcdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >4r9hB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpcdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4r9hC (C:)
miqrtpkiqvysrhpaengksnflncyvsgfhpcdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >4r9hC (C:)
iqrtpkiqvysrhpaengksnflncyvsgfhpcdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrd

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4r9hD (D:)
miqrtpkiqvysrhpaengksnflncyvsgfhpcdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >4r9hD (D:)
miqrtpkiqvysrhpaengksnflncyvsgfhpcdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdr