PDB entry 4r4t

View 4r4t on RCSB PDB site
Description: Crystal Structure of RPA70N in complex with 5-(4-((4-(5-carboxyfuran-2-yl)phenylthioamido)methyl)phenyl)-1-(3,4-dichlorophenyl)-1H-pyrazole-3-carboxylic acid
Class: Protein binding
Keywords: OB-fold, Protein-Protein Interaction, Protein binding
Deposited on 2014-08-19, released 2014-11-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-03-11, with a file datestamp of 2015-03-06.
Experiment type: XRAY
Resolution: 1.28 Å
R-factor: N/A
AEROSPACI score: 0.6 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Replication protein A 70 kDa DNA-binding subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RPA1, REPA1, RPA70
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27694 (3-122)
      • expression tag (1-2)
      • engineered mutation (9)
    Domains in SCOPe 2.08: d4r4ta1, d4r4ta2
  • Heterogens: 3J0, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4r4tA (A:)
gshmvgqlsrgaiaaimqkgdtnikpilqvinirpittgnsppryrllmsdglntlssfm
latqlnplveeeqlssncvcqihrfivntlkdgrrvvilmelevlksaeavgvkignpvp
yne

    Sequence, based on observed residues (ATOM records): (download) 
    >4r4tA (A:)
shmvgqlsrgaiaaimqkgdtnikpilqvinirpittgnsppryrllmsdglntlssfml
atqlnplveeeqlssncvcqihrfivntlkdgrrvvilmelevlksaeavgvkignpvpy
ne