PDB entry 4qre

View 4qre on RCSB PDB site
Description: Structure of Methionyl-tRNA Synthetase in complex with 1-(4-{4-[(1H-benzimidazol-2-ylmethyl)amino]-6-(4,5-dimethoxy-2-methylphenoxy)pyrimidin-2-yl}piperazin-1-yl)ethanone
Class: ligase/ligase inhibitor
Keywords: protein synthesis, aminoacyl-tRNA synthetase, aminoacylation, cytosol, LIGASE-LIGASE INHIBITOR complex
Deposited on 2014-06-30, released 2015-07-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-07-29, with a file datestamp of 2015-07-24.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Methionyl-tRNA synthetase
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: metG, CH52_03385
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4qrea1, d4qrea2
  • Heterogens: 3BG, ATP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4qreA (A:)
mghhhhhhdydipttenlyfqgahmasmaketfyittpiyypsgnlhighaystvagdvi
arykrmqgydvryltgtdehgqkiqekaqkagkteieyldemiagikqlwakleisnddf
irtteerhkhvveqvferllkqgdiylgeyegwysvpdetyytesqlvdpqyengkiigg
kspdsghevelvkeesyffniskytdrllefydqnpdfiqppsrkneminnfikpgladl
avsrtsfnwgvhvpsnpkhvvyvwidalvnyisalgylsddeslfnkywpadihlmakei
vrfhsiiwpillmaldlplpkkvfahgwilmkdgkmskskgnvvdpnilidrygldatry
ylmrelpfgsdgvftpeafvertnfdlandlgnlvnrtismvnkyfdgelpayqgplhel
deemeamaletvksytesmeslqfsvalstvwkfisrtnkyidettpwvlakddsqkdml
gnvmahlveniryaavllrpflthapkeifeqlninnpqfmefssleqygvltesimvtg
qpkpifp

    Sequence, based on observed residues (ATOM records): (download) 
    >4qreA (A:)
aketfyittpiyypsgnlhighaystvagdviarykrmqgydvryltgtdehgqkiqeka
qkagkteieyldemiagikqlwakleisnddfirtteerhkhvveqvferllkqgdiylg
eyegwysvpdetyytesqlvdpqyengkiiggkspdsghevelvkeesyffniskytdrl
lefydqnpdfiqppsrkneminnfikpgladlavsrtsfnwgvhvpsnpkhvvyvwidal
vnyisalgylsddeslfnkywpadihlmakeivrfhsiiwpillmaldlplpkkvfahgw
ilmkdgkmskskgnvvdpnilidrygldatryylmrelpfgsdgvftpeafvertnfdla
ndlgnlvnrtismvnkyfdgelpayqgplheldeemeamaletvksytesmeslqfsval
stvwkfisrtnkyidettpwvlakddsqkdmlgnvmahlveniryaavllrpflthapke
ifeqlninnpqfmefssleqygvltesimvtgqpkpifp