PDB entry 4qr3

View 4qr3 on RCSB PDB site
Description: Brd4 Bromodomain 1 complex with its novel inhibitors
Class: transcription/transcription inhibitor
Keywords: BRD4, Bromodomain, four alpha helices, TRANSCRIPTION-TRANSCRIPTION INHIBITOR complex
Deposited on 2014-06-30, released 2015-07-01
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-07-01, with a file datestamp of 2015-06-26.
Experiment type: XRAY
Resolution: 1.37 Å
R-factor: N/A
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD4, HUNK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60885 (2-124)
      • expression tag (0-1)
    Domains in SCOPe 2.05: d4qr3a_
  • Heterogens: BNJ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4qr3A (A:)
    smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
    ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
    nelpt