PDB entry 4qgh

View 4qgh on RCSB PDB site
Description: S.aureus TMK in complex with potent inhibitor compound 47
Class: transferase/transferase inhibitor
Keywords: thymidine monphosphate, soluble, TRANSFERASE-TRANSFERASE INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2014-05-22, released 2014-06-11
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-07-02, with a file datestamp of 2014-06-27.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: 0.178
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thymidylate kinase
    Species: Staphylococcus aureus subsp. aureus [TaxId:282458]
    Gene: SAR0483, tmk
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4qgha_
  • Chain 'B':
    Compound: thymidylate kinase
    Species: Staphylococcus aureus subsp. aureus [TaxId:282458]
    Gene: SAR0483, tmk
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4qghb_
  • Heterogens: 32E, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4qghA (A:)
msafitfegpegsgkttvinevyhrlvkdydvimtrepggvptgeeirkivlegndmdir
teamlfaasrrehlvlkvipalkegkvvlcdryidsslayqgyargigveevralnefai
nglypdltiylnvsaevgreriiknsrdqnrldqedlkfhekviegyqeiihnesqrfks
vnadqplenvvedtyqtiikyleki

    Sequence, based on observed residues (ATOM records): (download) 
    >4qghA (A:)
safitfegpegsgkttvinevyhrlvkdydvimtrepggvptgeeirkivlegndmdirt
eamlfaasrrehlvlkvipalkegkvvlcdryidsslayqgyargigveevralnefain
glypdltiylnvsaevgreriikndqedlkfhekviegyqeiihnqrfksvnadqplenv
vedtyqtiikyleki

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4qghB (B:)
msafitfegpegsgkttvinevyhrlvkdydvimtrepggvptgeeirkivlegndmdir
teamlfaasrrehlvlkvipalkegkvvlcdryidsslayqgyargigveevralnefai
nglypdltiylnvsaevgreriiknsrdqnrldqedlkfhekviegyqeiihnesqrfks
vnadqplenvvedtyqtiikyleki

    Sequence, based on observed residues (ATOM records): (download) 
    >4qghB (B:)
safitfegpegsgkttvinevyhrlvkdydvimtrepggvptgeeirkivlegndmdirt
eamlfaasrrehlvlkvipalkegkvvlcdryidsslayqgyargigveevralnefain
glypdltiylnvsaevgreriikrldqedlkfhekviegyqeiihnesqrfksvnadqpl
envvedtyqtiikyleki