PDB entry 4qbc

View 4qbc on RCSB PDB site
Description: Crystal structure of C117T mutant of human acidic fibroblast growth factor in sodium formate buffer
Class: protein binding
Keywords: Beta-trefoil, growth factor, FGFR binding, heparin binding, PROTEIN BINDING
Deposited on 2014-05-07, released 2015-03-11
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-03-11, with a file datestamp of 2015-03-06.
Experiment type: XRAY
Resolution: 1.52 Å
R-factor: N/A
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: fibroblast growth factor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: FGF1, FGFA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05230
      • engineered mutation (122)
    Domains in SCOPe 2.06: d4qbca1, d4qbca2
  • Chain 'B':
    Compound: fibroblast growth factor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: FGF1, FGFA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05230
      • engineered mutation (122)
    Domains in SCOPe 2.06: d4qbcb1, d4qbcb2
  • Heterogens: SO4, FMT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4qbcA (A:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
yikstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkn
gstkrgprthygqkailflplpvssd

    Sequence, based on observed residues (ATOM records): (download) 
    >4qbcA (A:)
hhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevyi
kstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkngs
tkrgprthygqkailflplpv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4qbcB (B:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
yikstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkn
gstkrgprthygqkailflplpvssd

    Sequence, based on observed residues (ATOM records): (download) 
    >4qbcB (B:)
hhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevy
ikstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkng
stkrgprthygqkailflplpv