PDB entry 4qb3

View 4qb3 on RCSB PDB site
Description: Crystal structure of the first bromodomain of human BRD4 in complex with Olinone
Class: transcription/transcription inhibitor
Keywords: bromodomain, transcription factor, acetyl-lysine binding, TRANSCRIPTION-TRANSCRIPTION INHIBITOR complex
Deposited on 2014-05-06, released 2015-04-22
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-04-22, with a file datestamp of 2015-04-17.
Experiment type: XRAY
Resolution: 0.94 Å
R-factor: N/A
AEROSPACI score: 0.89 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Bromodomain-containing protein 4
  Species: Homo sapiens [TaxId:9606]
  Gene: BRD4, HUNK1
  Database cross-references and differences (RAF-indexed):
  • Uniprot O60885 (2-126)
    • expression tag (0-1)
  Domains in SCOPe 2.07: d4qb3a1, d4qb3a2
• Heterogens: 30M, EDO, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4qb3A (A:)
  smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
  ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
  nelptee