PDB entry 4qah
View 4qah on RCSB PDB site
Description: The second sphere residue T263 is important for function and activity of PTP1B through modulating WPD loop
Class: hydrolase
Keywords: Tyrosine phosphorylation, HYDROLASE
Deposited on
2014-05-05, released
2014-12-24
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-02-07, with a file datestamp of
2018-02-02.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.23
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: tyrosine-protein phosphatase non-receptor type 1
Species: Homo sapiens [TaxId:9606]
Gene: PTPN1, PTP1B
Database cross-references and differences (RAF-indexed):
- Uniprot P18031 (0-298)
- engineered mutation (262)
Domains in SCOPe 2.08: d4qaha_ - Heterogens: TRS, HOH