PDB entry 4pwh
View 4pwh on RCSB PDB site
Description: Crystal structure of V30M mutant human transthyretin complexed with caffeic acid 1,1-dimethylallyl ester
Class: transport protein
Keywords: transporter, thyroxine binding, TRANSPORT PROTEIN
Deposited on
2014-03-20, released
2014-11-26
The last revision prior to the SCOPe 2.08 freeze date was dated
2014-11-26, with a file datestamp of
2014-11-21.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.182
AEROSPACI score: 0.44
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4pwha_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4pwhb_ - Heterogens: PWH, CA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4pwhA (A:)
mrgshhhhhhgsmashrllllclaglvfvseagptgtgeskcplmvkvldavrgspainv
amhvfrkaaddtwepfasgktsesgelhgltteeefvegiykveidtksywkalgispfh
ehaevvftandsgprrytiaallspysysttavvtnpke
Sequence, based on observed residues (ATOM records): (download)
>4pwhA (A:)
cplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4pwhB (B:)
mrgshhhhhhgsmashrllllclaglvfvseagptgtgeskcplmvkvldavrgspainv
amhvfrkaaddtwepfasgktsesgelhgltteeefvegiykveidtksywkalgispfh
ehaevvftandsgprrytiaallspysysttavvtnpke
Sequence, based on observed residues (ATOM records): (download)
>4pwhB (B:)
cplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandprrytiaallspysysttavvtn