PDB entry 4pm7

View 4pm7 on RCSB PDB site
Description: Crystal structure of CTX-M-14 S70G:S237A in complex with cefotaxime at 1.29 Angstroms resolution
Class: hydrolase/antibiotic
Keywords: Class A beta-lactamase, cefotaxime, HYDROLASE-ANTIBIOTIC complex
Deposited on 2014-05-20, released 2014-12-31
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-12-31, with a file datestamp of 2014-12-26.
Experiment type: XRAY
Resolution: 1.29 Å
R-factor: 0.162
AEROSPACI score: 0.68 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-lactamase CTX-M-14
    Species: Klebsiella pneumoniae subsp. pneumoniae [TaxId:1125630]
    Gene: KPHS_p301310
    Database cross-references and differences (RAF-indexed):
    • Uniprot G8XD06 (0-262)
      • engineered mutation (44)
      • engineered mutation (211)
    Domains in SCOPe 2.05: d4pm7a_
  • Heterogens: CE3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4pm7A (A:)
    qtsavqqklaalekssggrlgvalidtadntqvlyrgderfpmcgtskvmaaaavlkqse
    tqkqllnqpveikpadlvnynpiaekhvngtmtlaelsaaalqysdntamnkliaqlggp
    ggvtafaraigdetfrldrteptlntaipgdprdtttpramaqtlrqltlghalgetqra
    qlvtwlkgnttgaasiraglptswtvgdktgagdygttndiaviwpqgraplvlvtyftq
    pqqnaesrrdvlasaariiaegl