PDB entry 4pjb

View 4pjb on RCSB PDB site
Description: Structure of human MR1-5-OP-RU in complex with human MAIT B-F3-C1 TCR
Class: immune system
Keywords: MR1, TCR, Immune complex, 5-OP-RU, IMMUNE SYSTEM
Deposited on 2014-05-12, released 2014-07-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-10-01, with a file datestamp of 2014-09-26.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: 0.168
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-End)
      • initiating methionine (0)
      • engineered mutation (261)
    Domains in SCOPe 2.07: d4pjba1, d4pjba2, d4pjba3
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4pjbb_
  • Chain 'C':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-End)
      • initiating methionine (0)
      • engineered mutation (261)
    Domains in SCOPe 2.07: d4pjbc1, d4pjbc2, d4pjbc3
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4pjbd_
  • Chain 'E':
    Compound: TCR-alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PJB
    Domains in SCOPe 2.07: d4pjbe1, d4pjbe2
  • Chain 'F':
    Compound: TCR-beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PJB
    Domains in SCOPe 2.07: d4pjbf1, d4pjbf2
  • Chain 'G':
    Compound: TCR-alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PJB
    Domains in SCOPe 2.07: d4pjbg1, d4pjbg2
  • Chain 'H':
    Compound: TCR-beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PJB
    Domains in SCOPe 2.07: d4pjbh1, d4pjbh2
  • Heterogens: 2LJ, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4pjbA (A:)
    mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
    erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
    lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
    epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
    awasieldpqssnlyschvehsgvhmvlqvp
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pjbA (A:)
    mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
    erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
    lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
    epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
    awasiellyschvehsgvhmvlqv
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4pjbB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pjbB (B:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwd
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4pjbC (C:)
    mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
    erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
    lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
    epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
    awasieldpqssnlyschvehsgvhmvlqvp
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pjbC (C:)
    mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
    erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
    lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
    epplvrvnrkevtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyqawas
    iellyschvehsgvhmvlqv
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4pjbD (D:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pjbD (D:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwd
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >4pjbE (E:)
    hmgqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekg
    rfssflsrskgysylllkelqmkdsasylcasidsnyqliwgagtkliikpdiqnpdpav
    yqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnks
    dfacanafnnsiipedtffpspess
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pjbE (E:)
    qnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrfs
    sflsrskgysylllkelqmkdsasylcasidsnyqliwgagtkliikpdiqnpdpavyql
    rsvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsndfacanafnnsi
    ipedtffp
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >4pjbF (F:)
    hmnagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkg
    evpngynvsrlnkrefslrlesaapsqtsvyfcassetdpntgelffgegsrltvledlk
    nvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplk
    eqpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsae
    awgrad
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pjbF (F:)
    gvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgevpn
    gynvsrlnkrefslrlesaapsqtsvyfcassetdpntgelffgegsrltvledlknvfp
    pevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpa
    lndsryalssrlrvsatfwqrcqvqfyglsendewtqdrakpvtqivsae
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >4pjbG (G:)
    hmgqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekg
    rfssflsrskgysylllkelqmkdsasylcasidsnyqliwgagtkliikpdiqnpdpav
    yqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnks
    dfacanafnnsiipedtffpspess
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pjbG (G:)
    qnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrfs
    sflsrskgysylllkelqmkdsasylcasidsnyqliwgagtkliikpdiqnpdpavyql
    rdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdfa
    canafnnsiipedtffp
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >4pjbH (H:)
    hmnagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkg
    evpngynvsrlnkrefslrlesaapsqtsvyfcassetdpntgelffgegsrltvledlk
    nvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplk
    eqpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsae
    awgrad
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pjbH (H:)
    gvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgevpn
    gynvsrlnkrefslrlesaapsqtsvyfcassetdpntgelffgegsrltvledlknvfp
    pevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpa
    lndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeaw