PDB entry 4pj9

View 4pj9 on RCSB PDB site
Description: Structure of human MR1-5-OP-RU in complex with human MAIT TRAJ20 TCR
Class: immune system
Keywords: MR1, TCR, Immune complex, 5-OP-RU, IMMUNE SYSTEM
Deposited on 2014-05-12, released 2014-07-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-10-01, with a file datestamp of 2014-09-26.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.174
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-270)
      • initiating methionine (0)
      • engineered mutation (261)
    Domains in SCOPe 2.07: d4pj9a1, d4pj9a2, d4pj9a3
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-End)
      • initiating methionine (0)
    Domains in SCOPe 2.07: d4pj9b1, d4pj9b2
  • Chain 'C':
    Compound: TCR-alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PJ9
    Domains in SCOPe 2.07: d4pj9c1, d4pj9c2
  • Chain 'D':
    Compound: TCR-beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PJ9
    Domains in SCOPe 2.07: d4pj9d1, d4pj9d2
  • Heterogens: 2LJ, GOL, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4pj9A (A:)
    mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
    erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
    lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
    epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
    awasieldpqssnlyschvehsgvhmvlqvp
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pj9A (A:)
    mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
    erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
    lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
    epplvrvnrkgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyqawas
    ielnlyschvehsgvhmvlqvp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4pj9B (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pj9B (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdr
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4pj9C (C:)
    gqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrf
    ssflsrskgysylllkelqmkdsasylcavrdgdyklsfgagttvtvraniqnpdpavyq
    lrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdf
    acanafnnsiipedtffpspess
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pj9C (C:)
    qnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrfs
    sflsrskgysylllkelqmkdsasylcavrdgdyklsfgagttvtvraniqnpdpavyql
    rdsksksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsacanafnn
    siipedtffp
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4pj9D (D:)
    iagitqaptsqilaagrrmtlrctqdmrhnamywyrqdlglglrlihysntagttgkgev
    pdgysvsrantddfpltlasavpsqtsvyfcassagastgelffgegsrltvledlknvf
    ppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqp
    alndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg
    rad
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pj9D (D:)
    agitqaptsqilaagrrmtlrctqdmrhnamywyrqdlglglrlihysntagttgkgevp
    dgysvsrantddfpltlasavpsqtsvyfcassagastgelffgegsrltvledlknvfp
    pevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpa
    lndsryalssrlrvsatfwqnprnhfrcqvqfygldrakpvtqivsaeaw