PDB entry 4p5m
View 4p5m on RCSB PDB site
Description: Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergic Hypersensitivity and Autoimmunity
Class: immune system
Keywords: CBD, autoimmunity, beryllium, IMMUNE SYSTEM
Deposited on
2014-03-18, released
2014-08-27
The last revision prior to the SCOPe 2.06 freeze date was dated
2015-10-14, with a file datestamp of
2015-10-09.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: HLA class II histocompatibility antigen, DP alpha 1 chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-DPA1, HLA-DP1A, HLASB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4p5ma1, d4p5ma2 - Chain 'B':
Compound: peptide,HLA class II histocompatibility antigen, DP beta 1 chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-DPB1
Database cross-references and differences (RAF-indexed):
- PDB 4P5M (0-11)
- Uniprot Q5EP54 (Start-211)
- Chain 'C':
Compound: HLA class II histocompatibility antigen, DP alpha 1 chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-DPA1, HLA-DP1A, HLASB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4p5mc1, d4p5mc2 - Chain 'D':
Compound: peptide,HLA class II histocompatibility antigen, DP beta 1 chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-DPB1
Database cross-references and differences (RAF-indexed):
- PDB 4P5M (0-11)
- Uniprot Q5EP54 (Start-211)
- Chain 'E':
Compound: HLA class II histocompatibility antigen, DP alpha 1 chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-DPA1, HLA-DP1A, HLASB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4p5me1, d4p5me2 - Chain 'F':
Compound: peptide,HLA class II histocompatibility antigen, DP beta 1 chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-DPB1
Database cross-references and differences (RAF-indexed):
- PDB 4P5M (0-11)
- Uniprot Q5EP54
- Chain 'G':
Compound: HLA class II histocompatibility antigen, DP alpha 1 chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-DPA1, HLA-DP1A, HLASB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4p5mg1, d4p5mg2 - Chain 'H':
Compound: peptide,HLA class II histocompatibility antigen, DP beta 1 chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-DPB1
Database cross-references and differences (RAF-indexed):
- PDB 4P5M (0-11)
- Uniprot Q5EP54 (25-End)
- Heterogens: NA, NAG, BMA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4p5mA (A:)
ikadhvstyaafvqthrptgefmfefdedemfyvdldkketvwhleefgqafsfeaqggl
aniailnnnlntliqrsnhtqatndppevtvfpkepvelgqpntlichidkffppvlnvt
wlcngelvtegvaeslflprtdysfhkfhyltfvpsaedfydcrvehwgldqpllkhwea
qep
Sequence, based on observed residues (ATOM records): (download)
>4p5mA (A:)
ikadhvstyaafvqthrptgefmfefdedemfyvdldkketvwhleefgqafsfeaqggl
aniailnnnlntliqrsnhtqatndppevtvfpkepvelgqpntlichidkffppvlnvt
wlcngelvtegvaeslflprtdysfhkfhyltfvpsaedfydcrvehwgldqpllkhwea
- Chain 'B':
No sequence available.
- Chain 'C':
Sequence, based on SEQRES records: (download)
>4p5mC (C:)
ikadhvstyaafvqthrptgefmfefdedemfyvdldkketvwhleefgqafsfeaqggl
aniailnnnlntliqrsnhtqatndppevtvfpkepvelgqpntlichidkffppvlnvt
wlcngelvtegvaeslflprtdysfhkfhyltfvpsaedfydcrvehwgldqpllkhwea
qep
Sequence, based on observed residues (ATOM records): (download)
>4p5mC (C:)
ikadhvstyaafvqthrptgefmfefdedemfyvdldkketvwhleefgqafsfeaqggl
aniailnnnlntliqrsnhtqatndppevtvfpkepvelgqpntlichidkffppvlnvt
wlcngelvtegvaeslflprtdysfhkfhyltfvpsaedfydcrvehwgldqpllkhwea
- Chain 'D':
No sequence available.
- Chain 'E':
Sequence, based on SEQRES records: (download)
>4p5mE (E:)
ikadhvstyaafvqthrptgefmfefdedemfyvdldkketvwhleefgqafsfeaqggl
aniailnnnlntliqrsnhtqatndppevtvfpkepvelgqpntlichidkffppvlnvt
wlcngelvtegvaeslflprtdysfhkfhyltfvpsaedfydcrvehwgldqpllkhwea
qep
Sequence, based on observed residues (ATOM records): (download)
>4p5mE (E:)
ikadhvstyaafvqthrptgefmfefdedemfyvdldkketvwhleefgqafsfeaqggl
aniailnnnlntliqrsnhtqatndppevtvfpkepvelgqpntlichidkffppvlnvt
wlcngelvtegvaeslflprtdysfhkfhyltfvpsaedfydcrvehwgldqpllkhwea
- Chain 'F':
No sequence available.
- Chain 'G':
Sequence, based on SEQRES records: (download)
>4p5mG (G:)
ikadhvstyaafvqthrptgefmfefdedemfyvdldkketvwhleefgqafsfeaqggl
aniailnnnlntliqrsnhtqatndppevtvfpkepvelgqpntlichidkffppvlnvt
wlcngelvtegvaeslflprtdysfhkfhyltfvpsaedfydcrvehwgldqpllkhwea
qep
Sequence, based on observed residues (ATOM records): (download)
>4p5mG (G:)
ikadhvstyaafvqthrptgefmfefdedemfyvdldkketvwhleefgqafsfeaqggl
aniailnnnlntliqrsnhtqatndppevtvfpkepvelgqpntlichidkffppvlnvt
wlcngelvtegvaeslflprtdysfhkfhyltfvpsaedfydcrvehwgldqpllkhwea
- Chain 'H':
No sequence available.