PDB entry 4oru

View 4oru on RCSB PDB site
Description: Three-dimensional structure of the C65A mutant of Human lipocalin-type Prostaglandin D Synthase holo-form second space group
Class: isomerase
Keywords: lipocalin-type prostaglandin-d synthase, peg, isomerase
Deposited on 2014-02-12, released 2014-08-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-12-17, with a file datestamp of 2014-12-12.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: 0.21
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Prostaglandin-H2 D-isomerase
    Species: Homo sapiens [TaxId:9606]
    Gene: PTGDS, PDS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41222
      • engineered mutation (64)
    Domains in SCOPe 2.08: d4orua_
  • Chain 'B':
    Compound: Prostaglandin-H2 D-isomerase
    Species: Homo sapiens [TaxId:9606]
    Gene: PTGDS, PDS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41222
      • engineered mutation (64)
    Domains in SCOPe 2.08: d4orub_
  • Heterogens: PEU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4oruA (A:)
mathhtlwmglallgvlgdlqaapeaqvsvqpnfqqdkflgrwfsaglasnsswlrekka
alsmaksvvapatdgglnltstflrknqcetrtmllqpagslgsysyrsphwgstysvsv
vetdydqyallysqgskgpgedfrmatlysrtqtpraelkekftafckaqgftedtivfl
pqtdkcmteq

    Sequence, based on observed residues (ATOM records): (download) 
    >4oruA (A:)
svqpnfqqdkflgrwfsaglasnsswlrekkaalsmaksvvapatdgglnltstflrknq
cetrtmllqpagslgsysyrsphwgstysvsvvetdydqyallysqgskgpgedfrmatl
ysrtqtpraelkekftafckaqgftedtivflpqtdkcm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4oruB (B:)
mathhtlwmglallgvlgdlqaapeaqvsvqpnfqqdkflgrwfsaglasnsswlrekka
alsmaksvvapatdgglnltstflrknqcetrtmllqpagslgsysyrsphwgstysvsv
vetdydqyallysqgskgpgedfrmatlysrtqtpraelkekftafckaqgftedtivfl
pqtdkcmteq

    Sequence, based on observed residues (ATOM records): (download) 
    >4oruB (B:)
svqpnfqqdkflgrwfsaglasnsswlrekkaalsmaksvvapatdgglnltstflrknq
cetrtmllqpagslgsysyrsphwgstysvsvvetdydqyallysqgskgpgedfrmatl
ysrtqtpraelkekftafckaqgftedtivflpqtdkcm