PDB entry 4org

View 4org on RCSB PDB site
Description: Crystal structure of human Fab CAP256-VRC26.04, a potent V1V2-directed HIV-1 neutralizing antibody
Class: immune system
Keywords: Fab, HIV-1, V1V2, CAP256, VRC26, IMMUNE SYSTEM
Deposited on 2014-02-11, released 2014-02-26
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-05-14, with a file datestamp of 2014-05-09.
Experiment type: XRAY
Resolution: 3.12 Å
R-factor: 0.276
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: CAP256-VRC26.04 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4ORG
  • Chain 'B':
    Compound: CAP256-VRC26.04 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4ORG
    Domains in SCOPe 2.05: d4orgb1, d4orgb2
  • Chain 'C':
    Compound: CAP256-VRC26.04 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4ORG
  • Chain 'D':
    Compound: CAP256-VRC26.04 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4ORG
    Domains in SCOPe 2.05: d4orgd1, d4orgd2
  • Chain 'E':
    Compound: CAP256-VRC26.04 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4ORG
  • Chain 'F':
    Compound: CAP256-VRC26.04 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4ORG
    Domains in SCOPe 2.05: d4orgf1, d4orgf2
  • Chain 'H':
    Compound: CAP256-VRC26.04 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4ORG
  • Chain 'L':
    Compound: CAP256-VRC26.04 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4ORG
    Domains in SCOPe 2.05: d4orgl1, d4orgl2

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4orgB (B:)
pvltqppsvsaapgqkvtiscsgsssnignnfvswyqqrpgtapslliyetnkrpsgipd
rfsgsksatsatlaitglqtgdeadyycatwaasltsarvfgtgtkvivsgqpkanptvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >4orgB (B:)
vltqppsvsaapgqkvtiscsgsssnignnfvswyqqrpgtapslliyetnkrpsgipdr
fsgsksatsatlaitglqtgdeadyycatwltsarvfgtgtkvivsgqpkanptvtlfpp
sseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassylsl
tpeqwkshrsyscqvthegstvektvap

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4orgD (D:)
pvltqppsvsaapgqkvtiscsgsssnignnfvswyqqrpgtapslliyetnkrpsgipd
rfsgsksatsatlaitglqtgdeadyycatwaasltsarvfgtgtkvivsgqpkanptvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >4orgD (D:)
vltqppsvsaapgqkvtiscsgsssnignnfvswyqqrpgtapslliyetnkrpsgipdr
fsgsksatsatlaitglqtgdeadyycatwaaslvfgtgtkvivsgqpkanptvtlfpps
seelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassylslt
peqwkshrsyscqvthegstvektvapt

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4orgF (F:)
pvltqppsvsaapgqkvtiscsgsssnignnfvswyqqrpgtapslliyetnkrpsgipd
rfsgsksatsatlaitglqtgdeadyycatwaasltsarvfgtgtkvivsgqpkanptvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >4orgF (F:)
vltqppsvsaapgqkvtiscsgsssnignnfvswyqqrpgtapslliyetnkrpsgipdr
fsgsksatsatlaitglqtgdeadyycatwaaslvfgtgtkvivsgqpkanptvtlfpps
seelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassylslt
peqwkshrsyscqvthegstvektvapte

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >4orgL (L:)
pvltqppsvsaapgqkvtiscsgsssnignnfvswyqqrpgtapslliyetnkrpsgipd
rfsgsksatsatlaitglqtgdeadyycatwaasltsarvfgtgtkvivsgqpkanptvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >4orgL (L:)
vltqppsvsaapgqkvtiscsgsssnignnfvswyqqrpgtapslliyetnkrpsgipdr
fsgsksatsatlaitglqtgdeadyycatwaasltsarvfgtgtkvivsgqpkanptvtl
fppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassy
lsltpeqwkshrsyscqvthegstvektvap