PDB entry 4ol0

View 4ol0 on RCSB PDB site
Description: Crystal structure of transportin-SR2, a karyopherin involved in human disease, in complex with Ran
Class: protein transport
Keywords: Human Karyopherins, Active Transport, Nucleus, ran GTP-Binding Protein, PROTEIN TRANSPORT
Deposited on 2014-01-23, released 2014-04-09
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-06-25, with a file datestamp of 2014-06-20.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.224
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTP-binding nuclear protein ran
    Species: Homo sapiens [TaxId:9606]
    Gene: RAN, ARA24, OK/SW-cl.81
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4ol0a_
  • Chain 'B':
    Compound: transportin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: TNPO3, IPO12
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MG, GTP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ol0A (A:)
maaqgepqvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpik
fnvwdtagqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlc
gnkvdikdrkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefvamp
alappevvmdpalaaqyehdlevaqttalpdedddl

    Sequence, based on observed residues (ATOM records): (download) 
    >4ol0A (A:)
qvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpikfnvwdta
gqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkvdik
drkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefvam

  • Chain 'B':
    No sequence available.