PDB entry 4o78
View 4o78 on RCSB PDB site
Description: Crystal structure of the first bromodomain of human BRD4 in complex with GW612286X
Class: transcription/inhibitor
Keywords: BROMODOMAIN, CAP, HUNK1, MCAP, PROTEIN BINDING-INHIBITOR COMPLEX, MITOTIC CHROMOSOME ASSOCIATED PROTEIN, CELL CYCLE, INHIBITOR, TRANSCRIPTION-INHIBITOR complex
Deposited on
2013-12-24, released
2014-03-05
The last revision prior to the SCOPe 2.06 freeze date was dated
2014-05-28, with a file datestamp of
2014-05-23.
Experiment type: XRAY
Resolution: 1.34 Å
R-factor: 0.119
AEROSPACI score: 0.71
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Bromodomain-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: BRD4, HUNK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4o78a1, d4o78a2 - Heterogens: SAV, EDO, PGE, CL, HOH