PDB entry 4nxz

View 4nxz on RCSB PDB site
Description: DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable TTP with manganese in the active site
Class: transferase, lyase/DNA
Keywords: DNA binding, DNA polymerase fold, nucleotidyl transfer, nucleolus, TRANSFERASE, LYASE-DNA complex
Deposited on 2013-12-09, released 2014-04-16
The last revision prior to the SCOPe 2.04 freeze date was dated 2014-07-02, with a file datestamp of 2014-06-27.
Experiment type: XRAY
Resolution: 2.56 Å
R-factor: 0.193
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase beta
    Species: Homo sapiens [TaxId:9606]
    Gene: POLB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4nxza1, d4nxza2, d4nxza3
  • Chain 'D':
    Compound: 5'-d(p*gp*tp*cp*gp*g)-3'
  • Chain 'P':
    Compound: 5'-d(*gp*cp*tp*gp*ap*tp*gp*cp*gp*a)-3'
  • Chain 'T':
    Compound: 5'-d(*cp*cp*gp*ap*cp*(6og)p*tp*cp*gp*cp*ap*tp*cp*ap*gp*c)-3'
  • Heterogens: MN, NA, 1FZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4nxzA (A:)
tlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeakklpgvgtki
aekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegiktledlrkne
dklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgsfrrgaessg
dmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcqlpskndeke
yphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirplgvtgvage
plpvdsekdifdyiqwkyrepkdrse

  • Chain 'D':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.