PDB entry 4nwu
View 4nwu on RCSB PDB site
Description: Crystal structure of APE1551, an anti-human NGF Fab with a nine amino acid insertion in CDR H1
Class: immune system
Keywords: beta-sandwich, human beta nerve growth factor, IMMUNE SYSTEM
Deposited on
2013-12-06, released
2014-10-22
The last revision prior to the SCOPe 2.05 freeze date was dated
2014-12-10, with a file datestamp of
2014-12-05.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.168
AEROSPACI score: 0.52
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: APE1551 Ab Fab heavy chain
Species: Homo sapiens [TaxId:9606]
Gene: IGHG1
Database cross-references and differences (RAF-indexed):
- PDB 4NWU (Start-144)
- Uniprot P01857 (145-End)
- Chain 'L':
Compound: APE1551 Ab Fab light chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 4NWU (0-110)
- Uniprot Q8TCD0 (111-219)
Domains in SCOPe 2.05: d4nwul1, d4nwul2 - Heterogens: HOH