PDB entry 4nr5

View 4nr5 on RCSB PDB site
Description: Crystal structure of the bromodomain of human CREBBP in complex with an isoxazolyl-benzimidazole ligand
Class: transcription/inhibitor
Keywords: Structural Genomics Consortium, SGC, chemical tool, small molecule inhibitor, transcription, TRANSCRIPTION-INHIBITOR complex
Deposited on 2013-11-26, released 2013-12-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-31, with a file datestamp of 2018-01-26.
Experiment type: XRAY
Resolution: 1.66 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: creb-binding protein
  Species: Homo sapiens [TaxId:9606]
  Gene: CBP, CREBBP
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q92793
  Domains in SCOPe 2.08: d4nr5a_
• Heterogens: 2LL, NO3, EDO, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >4nr5A (A:)
  smrkkifkpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivknpmdlsti
  krkldtgqyqepwqyvddvwlmfnnawlynrktsrvykfcsklaevfeqeidpvmqslg
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >4nr5A (A:)
  kifkpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivknpmdlstikrkl
  dtgqyqepwqyvddvwlmfnnawlynrktsrvykfcsklaevfeqeidpvmqs