PDB entry 4nr3

View 4nr3 on RCSB PDB site
Description: Crystal Structure of a human Mms2/Ubc13 L121G mutant
Class: ligase
Keywords: ubc13, mms2, E2, ubiquitin conjugating enzyme, ligase
Deposited on 2013-11-26, released 2014-12-10
The last revision prior to the SCOPe 2.04 freeze date was dated 2014-12-10, with a file datestamp of 2014-12-05.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.19
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin-conjugating enzyme E2 variant 2
    Species: Homo sapiens [TaxId:9606]
    Gene: MMS2, UBE2V2, UEV2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4nr3a_
  • Chain 'B':
    Compound: Ubiquitin-conjugating enzyme E2 N
    Species: Homo sapiens [TaxId:9606]
    Gene: BLU, UBE2N
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61088 (8-156)
      • engineered mutation (127)
    Domains in SCOPe 2.04: d4nr3b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4nr3A (A:)
gplgspefgvkvprnfrlleeleegqkgvgdgtvswgleddedmtltrwtgmiigpprtn
yenriyslkvecgpkypeappsvrfvtkinmnginnssgmvdarsipvlakwqnsysikv
vlqelrrlmmskenmklpqppegqtynn

    Sequence, based on observed residues (ATOM records): (download) 
    >4nr3A (A:)
gvkvprnfrlleeleegqkgvgdgtvswgleddedmtltrwtgmiigpprtnyenriysl
kvecgpkypeappsvrfvtkinmnginnssgmvdarsipvlakwqnsysikvvlqelrrl
mmskenmklpqppegqtynn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4nr3B (B:)
gplgspefaglprriiketqrllaepvpgikaepdesnaryfhvviagpqdspfeggtfk
lelflpeeypmaapkvrfmtkiyhpnvdklgricldilkdkwspalqirtvllsiqalls
apnpddpgandvaeqwktneaqaietarawtrlyamn

    Sequence, based on observed residues (ATOM records): (download) 
    >4nr3B (B:)
aglprriiketqrllaepvpgikaepdesnaryfhvviagpqdspfeggtfklelflpee
ypmaapkvrfmtkiyhpnvdklgricldilkdkwspalqirtvllsiqallsapnpddpg
andvaeqwktneaqaietarawtrlyamn