PDB entry 4nqt

View 4nqt on RCSB PDB site
Description: anti-parallel Fc-hole(T366S/L368A/Y407V) homodimer
Class: immune system
Keywords: immunoglobulin, IMMUNE SYSTEM
Deposited on 2013-11-25, released 2014-03-12
The last revision prior to the SCOPe 2.03 freeze date was dated 2014-03-12, with a file datestamp of 2014-03-07.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.198
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ig gamma-1 chain C region
    Species: Homo sapiens [TaxId:9606]
    Gene: IGHG1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01857
      • see remark 999 (121)
      • see remark 999 (123)
      • engineered mutation (131)
      • engineered mutation (133)
      • engineered mutation (172)
    Domains in SCOPe 2.03: d4nqta1, d4nqta2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4nqtA (A:)
    lggpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyvdgvevhnaktkpree
    qynstyrvvsvltvlhqdwlngkeykckvsnkalpapiektiskakgqprepqvytlpps
    reemtknqvslscavkgfypsdiavewesngqpennykttppvldsdgsfflvskltvdk
    srwqqgnvfscsvmhealhnhytqkslslspgk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4nqtA (A:)
    gpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyvdgvevhnaktkpreeqy
    nstyrvvsvltvlhqdwlngkeykckvsnkalpapiektiskakgqprepqvytlppsre
    emtknqvslscavkgfypsdiavewesngqpennykttppvldsdgsfflvskltvdksr
    wqqgnvfscsvmhealhnhytqkslsls