PDB entry 4nm2

View 4nm2 on RCSB PDB site
Description: Structure of human DNA polymerase beta complexed with a nicked DNA containing a 8BrG-G at N-1 position and G-C at N position
Class: transferase, lyase/DNA
Keywords: DNA binding, helix-turn-helix motif, polymerase fold, nucleotidyl transferase, nucleus, TRANSFERASE, LYASE-DNA complex
Deposited on 2013-11-14, released 2014-01-22
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-03-19, with a file datestamp of 2014-03-14.
Experiment type: XRAY
Resolution: 2.52 Å
R-factor: 0.204
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase beta
    Species: Homo sapiens [TaxId:9606]
    Gene: POLB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4nm2a1, d4nm2a2, d4nm2a3
  • Chain 'D':
    Compound: 5'-d(p*gp*tp*cp*gp*g)-3'
  • Chain 'P':
    Compound: 5'-d(*gp*cp*tp*gp*ap*tp*gp*cp*gp*gp*c)-3'
  • Chain 'T':
    Compound: 5'-d(*cp*cp*gp*ap*cp*gp*(bgm)p*cp*gp*cp*ap*tp*cp*ap*gp*c)-3'
  • Heterogens: NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4nm2A (A:)
pqetlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeakklpgvg
tkiaekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegiktledlr
knedklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgsfrrgae
ssgdmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcqlpsknd
ekeyphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirplgvtgv
ageplpvdsekdifdyiqwkyrepkdrse

    Sequence, based on observed residues (ATOM records): (download) 
    >4nm2A (A:)
nggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeakklpgvgtkiae
kideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegiktledlrknedk
lnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgsfrrgaessgdm
dvllthpsftsesqpkllhqvveqlqkvhfitdtlskgetkfmgvcqlpskdekeyphrr
idirlipkdqyycgvlyftgsdifnknmrahalekgftineytirplgvtgvageplpvd
sekdifdyiqwkyrepkdrse

  • Chain 'D':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.