PDB entry 4nm0
View 4nm0 on RCSB PDB site
Description: Crystal structure of peptide inhibitor-free GSK-3/Axin complex
Class: transferase/peptide
Keywords: Wnt, LRP6, Auto-inhibited, GSK-3, Axin, kinase, primed substrate, TRANSFERASE-PEPTIDE complex
Deposited on
2013-11-14, released
2014-03-26
The last revision prior to the SCOPe 2.04 freeze date was dated
2014-03-26, with a file datestamp of
2014-03-21.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.193
AEROSPACI score: 0.27
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Glycogen synthase kinase-3 beta
Species: Homo sapiens [TaxId:9606]
Gene: GSK3B
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4nm0a_ - Chain 'B':
Compound: Axin-1
Species: Homo sapiens [TaxId:9606]
Gene: AXIN, AXIN1
Database cross-references and differences (RAF-indexed):
- Heterogens: GOL, MG, ADP, DTT, CL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4nm0A (A:)
msgrprttsfaesckpvqqpsafgsmkvsrdkdgskvttvvatpgqgpdrpqevsytdtk
vigngsfgvvyqaklcdsgelvaikkvlqdkrfknrelqimrkldhcnivrlryffyssg
ekkdevylnlvldyvpetvyrvarhysrakqtlpviyvklymyqlfrslayihsfgichr
dikpqnllldpdtavlklcdfgsakqlvrgepnvsyicsryyrapelifgatdytssidv
wsagcvlaelllgqpifpgdsgvdqlveiikvlgtptreqiremnpnytefkfpqikahp
wtkvfrprtppeaialcsrlleytptarltpleacahsffdelrdpnvklpngrdtpalf
nfttqelssnpplatilippharhhhhhh
Sequence, based on observed residues (ATOM records): (download)
>4nm0A (A:)
mkvsrdskvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvl
qdkrfknrelqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrvarhysr
akqtlpviyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlv
rgepnvsyicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlve
iikvlgtptreqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleytptar
ltpleacahsffdelrdpnvklpngrdtpalfnfttqelssnpplatilippharh
- Chain 'B':
No sequence available.