PDB entry 4nlz

View 4nlz on RCSB PDB site
Description: Structure of human DNA polymerase beta complexed with nicked DNA containing a mismatched template 8BrG and incoming GTP
Class: transferase, lyase/DNA
Keywords: DNA binding, helix-turn-helix motif, polymerase fold, nucleotidyl transferase, nucleus, TRANSFERASE, LYASE-DNA complex
Deposited on 2013-11-14, released 2014-01-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-03-19, with a file datestamp of 2014-03-14.
Experiment type: XRAY
Resolution: 2.68 Å
R-factor: 0.204
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase beta
    Species: Homo sapiens [TaxId:9606]
    Gene: POLB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4nlza1, d4nlza2, d4nlza3
  • Chain 'D':
    Compound: 5'-d(p*gp*tp*cp*gp*g)-3'
  • Chain 'P':
    Compound: 5'-d(*gp*cp*tp*gp*ap*tp*gp*cp*gp*ap*g)-3'
  • Chain 'T':
    Compound: 5'-d(*cp*cp*gp*ap*cp*(bgm)p*tp*cp*gp*cp*ap*tp*cp*ap*gp*c)-3'
  • Heterogens: MG, NA, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4nlzA (A:)
pqetlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeakklpgvg
tkiaekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegiktledlr
knedklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgsfrrgae
ssgdmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcqlpsknd
ekeyphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirplgvtgv
ageplpvdsekdifdyiqwkyrepkdrse

    Sequence, based on observed residues (ATOM records): (download) 
    >4nlzA (A:)
etlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeakklpgvgtk
iaekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegiktledlrkn
edklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgsfrrgaess
gdmdvllthpsftsesqkllhqvveqlqkvhfitdtlskgetkfmgvcqlpskdekeyph
rridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirplgvtgvageplp
vdsekdifdyiqwkyrepkdrse

  • Chain 'D':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.