PDB entry 4nlr

View 4nlr on RCSB PDB site
Description: Poliovirus Polymerase - C290S Loop Mutant
Class: Viral Protein, hydrolase
Keywords: polymerase, RNA dependent RNA polymerase, RdRP, virus, Viral Protein, hydrolase
Deposited on 2013-11-14, released 2014-01-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-03-26, with a file datestamp of 2014-03-21.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.227
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RNA-directed RNA polymerase 3D-POL
    Species: Human poliovirus 1 [TaxId:12081]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03300 (0-460)
      • engineered mutation (289)
      • engineered mutation (445)
      • engineered mutation (454)
    Domains in SCOPe 2.08: d4nlra_
  • Heterogens: ACY, 1PE, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4nlrA (A:)
geiqwmrpskevgypiinapsktklepsafhyvfegvkepavltkndprlktdfeeaifs
kyvgnkitevdeymkeavdhyagqlmsldinteqmcledamygtdglealdlstsagypy
vamgkkkrdilnkqtrdtkemqklldtyginlplvtyvkdelrsktkveqgksrlieass
lndsvamrmafgnlyaafhknpgvitgsavgcdpdlfwskipvlmeeklfafdytgydas
lspawfealkmvlekigfgdrvdyidylnhshhlyknktycvkggmpsgssgtsifnsmi
nnliirtlllktykgidldhlkmiaygddviasyphevdasllaqsgkdygltmtpadks
atfetvtwenvtflkrffradekypflihpvmpmkeihesirwtkdprntqdhvrslcll
awhngeeeynkflakirsvpigraldlpeystlydrwldsf