PDB entry 4niv

View 4niv on RCSB PDB site
Description: Crystal structure of trypsiligase (K60E/N143H/Y151H/D189K trypsin) trigonal form
Class: hydrolase
Keywords: Trypsin, Serine proteinase, Enzyme design, Activation domain, Zymogen, Peptide ligation, Reverse proteolysis, HYDROLASE
Deposited on 2013-11-08, released 2014-02-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-03-19, with a file datestamp of 2014-03-14.
Experiment type: XRAY
Resolution: 1 Å
R-factor: 0.151
AEROSPACI score: 0.92 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cationic trypsin
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00760 (Start-222)
      • engineered mutation (42)
    Domains in SCOPe 2.07: d4niva_
  • Heterogens: CA, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4nivA (A:)
ivggytcgantvpyqvslnsgyhfcggslinsqwvvsaahcyesgiqvrlgedninvveg
neqfisasksivhpsynsntlnndimliklksaaslnsrvasislptscasagtqclisg
wghtkssgtshpdvlkclkapilsdsscksaypgqitsnmfcagyleggkkscqgdsggp
vvcsgklqgivswgsgcaqknkpgvytkvcnyvswikqtiasn

    Sequence, based on observed residues (ATOM records): (download) 
    >4nivA (A:)
ytcgantvpyqvslnsgyhfcggslinsqwvvsaahcyesgiqvrlgedninvvegneqf
isasksivhpsynsntlnndimliklksaaslnsrvasislptscasagtqclisgwpdv
lkclkapilsdsscksaypgqitsnmfcagydsggpvvcsgklqgivswgskpgvytkvc
nyvswikqtiasn