PDB entry 4ndn

View 4ndn on RCSB PDB site
Description: Structural insights of MAT enzymes: MATa2b complexed with SAM and PPNP
Class: transferase
Keywords: S-adenosylmethionine (SAMe) synthesis, TRANSFERASE
Deposited on 2013-10-27, released 2014-07-16
The last revision prior to the SCOPe 2.04 freeze date was dated 2014-07-23, with a file datestamp of 2014-07-18.
Experiment type: XRAY
Resolution: 2.34 Å
R-factor: 0.213
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: S-adenosylmethionine synthase isoform type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAT2A, AMS2, MATA2
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: S-adenosylmethionine synthase isoform type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAT2A, AMS2, MATA2
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: S-adenosylmethionine synthase isoform type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAT2A, AMS2, MATA2
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: S-adenosylmethionine synthase isoform type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAT2A, AMS2, MATA2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4ndnd1, d4ndnd2, d4ndnd3
  • Chain 'E':
    Compound: methionine adenosyltransferase 2 subunit beta
    Species: Homo sapiens [TaxId:9606]
    Gene: MAT2B, TGR, MSTP045, Nbla02999, UNQ2435/PRO4995
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4ndne_
  • Chain 'F':
    Compound: methionine adenosyltransferase 2 subunit beta
    Species: Homo sapiens [TaxId:9606]
    Gene: MAT2B, TGR, MSTP045, Nbla02999, UNQ2435/PRO4995
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MG, EDO, PPK, SAM, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4ndnD (D:)
mngqlngfheafieegtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetva
ktgmillageitsraavdyqkvvreavkhigyddsskgfdyktcnvlvaleqqspdiaqg
vhldrneedigagdqglmfgyatdeteecmpltivlahklnaklaelrrngtlpwlrpds
ktqvtvqymqdrgavlpirvhtivisvqhdeevcldemrdalkekvikavvpakyldedt
iyhlqpsgrfviggpqgdagltgrkiivdtyggwgahgggafsgkdytkvdrsaayaarw
vakslvkgglcrrvlvqvsyaigvshplsisifhygtsqkserelleivkknfdlrpgvi
vrdldlkkpiyqrtaayghfgrdsfpwevpkklky

    Sequence, based on observed residues (ATOM records): (download) 
    >4ndnD (D:)
eegtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetvaktgmillageits
raavdyqkvvreavkhigyddsskgfdyktcnvlvaleqqspdiaqgvhldrneedigag
dqglmfgyatdeteecmpltivlahklnaklaelrrngtlpwlrpdsktqvtvqymqdrg
avlpirvhtivisvqhdeevcldemrdalkekvikavvpakyldedtiyhlqpsgrfvig
gpqgdagltgrkiivdtyggwgahgggafsgkdytkvdrsaayaarwvakslvkgglcrr
vlvqvsyaigvshplsisifhygtsqkserelleivkknfdlrpgvivrdldlkkpiyqr
taayghfgrdsfpwevpkklky

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4ndnE (E:)
mpempedmeqeevnipnrrvlvtgatgllgravhkefqqnnwhavgcgfrrarpkfeqvn
lldsnavhhiihdfqphvivhcaaerrpdvvenqpdaasqlnvdasgnlakeaaavgafl
iyissdyvfdgtnppyreedipaplnlygktkldgekavlennlgaavlripilygevek
leesavtvmfdkvqfsnksanmdhwqqrfpthvkdvatvcrqlaekrmldpsikgtfhws
gneqmtkyemacaiadafnlpsshlrpitdspvlgaqrprnaqldcskletlgigqrtpf
rigikeslwpflidkrwrqtvfh

    Sequence, based on observed residues (ATOM records): (download) 
    >4ndnE (E:)
ipnrrvlvtgatgllgravhkefqqnnwhavgcgfrrarpkfeqvnlldsnavhhiihdf
qphvivhcaaerrpdvvenqpdaasqlnvdasgnlakeaaavgafliyissdyvfdgtnp
pyreedipaplnlygktkldgekavlennlgaavlripilygevekleesavtvmfdkvq
fsnksanmdhwqqrfpthvkdvatvcrqlaekrmldpsikgtfhwsgneqmtkyemacai
adafnlpsshlrpitdspvlgaqrprnaqldcskletlgigqrtpfrigikeslwpflid
krwrqtvfh

  • Chain 'F':
    No sequence available.