PDB entry 4n9l

View 4n9l on RCSB PDB site
Description: crystal structure of beta-lactamse PenP_E166S in complex with meropenem
Class: hydrolase/antibiotic
Keywords: hydrolase, HYDROLASE-ANTIBIOTIC complex
Deposited on 2013-10-21, released 2014-09-10
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-09-10, with a file datestamp of 2014-09-05.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.184
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Bacillus licheniformis [TaxId:1402]
    Gene: blaP, penP, penP blaP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00808
      • engineered mutation (140)
    Domains in SCOPe 2.06: d4n9la_
  • Chain 'B':
    Compound: Beta-lactamase
    Species: Bacillus licheniformis [TaxId:1402]
    Gene: blaP, penP, penP blaP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00808
      • engineered mutation (140)
    Domains in SCOPe 2.06: d4n9lb_
  • Heterogens: DWZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4n9lA (A:)
gpmktemkddfakleeqfdaklgifaldtgtnrtvayrpderfafastikaltvgvllqq
ksiedlnqritytrddlvnynpitekhvdtgmtlkeladaslrysdnaaqnlilkqiggp
eslkkelrkigdevtnperfspelnevnpgetqdtstaralvtslrafaledklpsekre
llidwmkrnttgdaliragvpdgwevadktgaasygtrndiaiiwppkgdpvvlavlssr
dkkdakyddkliaeatkvvmkalnmngk

    Sequence, based on observed residues (ATOM records): (download) 
    >4n9lA (A:)
ddfakleeqfdaklgifaldtgtnrtvayrpderfafastikaltvgvllqqksiedlnq
ritytrddlvnynpitekhvdtgmtlkeladaslrysdnaaqnlilkqiggpeslkkelr
kigdevtnperfspelnevnpgetqdtstaralvtslrafaledklpsekrellidwmkr
nttgdaliragvpdgwevadktgaasygtrndiaiiwppkgdpvvlavlssrdkkdakyd
dkliaeatkvvmkaln

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4n9lB (B:)
gpmktemkddfakleeqfdaklgifaldtgtnrtvayrpderfafastikaltvgvllqq
ksiedlnqritytrddlvnynpitekhvdtgmtlkeladaslrysdnaaqnlilkqiggp
eslkkelrkigdevtnperfspelnevnpgetqdtstaralvtslrafaledklpsekre
llidwmkrnttgdaliragvpdgwevadktgaasygtrndiaiiwppkgdpvvlavlssr
dkkdakyddkliaeatkvvmkalnmngk

    Sequence, based on observed residues (ATOM records): (download) 
    >4n9lB (B:)
ddfakleeqfdaklgifaldtgtnrtvayrpderfafastikaltvgvllqqksiedlnq
ritytrddlvnynpitekhvdtgmtlkeladaslrysdnaaqnlilkqiggpeslkkelr
kigdevtnperfspelnevnpgetqdtstaralvtslrafaledklpsekrellidwmkr
nttgdaliragvpdgwevadktgaasygtrndiaiiwppkgdpvvlavlssrdkkdakyd
dkliaeatkvvmkaln