PDB entry 4n46

View 4n46 on RCSB PDB site
Description: Crystal structure of thiolase from Clostridium acetobutylicum in complex with CoA
Class: transferase
Keywords: alpha/beta/alpha/beta/alpha domain, Acetyl-coA acetyltransferase, TRANSFERASE
Deposited on 2013-10-08, released 2014-10-08
Made obsolete by 4xl4 on 2015-10-07

The last revision prior to the SCOPe 2.05 freeze date was dated 2014-10-08, with a file datestamp of 2014-10-03.
Experiment type: XRAY
Resolution: 1.39 Å
R-factor: 0.192
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acetyl-CoA acetyltransferase
    Species: Clostridium acetobutylicum [TaxId:863638]
    Gene: CEA_G2880
    Database cross-references and differences (RAF-indexed):
    • Uniprot F0K5D8 (0-391)
      • engineered mutation (377)
    Domains in SCOPe 2.05: d4n46a1, d4n46a2
  • Chain 'B':
    Compound: Acetyl-CoA acetyltransferase
    Species: Clostridium acetobutylicum [TaxId:863638]
    Gene: CEA_G2880
    Database cross-references and differences (RAF-indexed):
    • Uniprot F0K5D8 (0-391)
      • engineered mutation (377)
    Domains in SCOPe 2.05: d4n46b1, d4n46b2
  • Heterogens: COA, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4n46A (A:)
mkevviasavrtaigsygkslkdvpavdlgataikeavkkagikpedvnevilgnvlqag
lgqnparqasfkaglpveipamtinkvcgsglrtvslaaqiikagdadviiaggmenmsr
apylannarwgyrmgnakfvdemitdglwdafndyhmgitaeniaerwnisreeqdefal
asqkkaeeaiksgqfkdeivpvvikgrkgetvvdtdehprfgstieglaklkpafkkdgt
vtagnasglndcaavlvimsaekakelgvkplakivsygsagvdpaimgygpfyatkaai
ekagwtvdeldliesneafaaqslavakdlkfdmnkvnvnggaialghpigasgarilvt
lvhamqkrdakkglatlsigggqgtaillekclehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4n46A (A:)
mkevviasavrtaigsygkslkdvpavdlgataikeavkkagikpedvnevilgnvlqag
lgqnparqasfkaglpveipamtinkvcgsglrtvslaaqiikagdadviiaggmenmsr
apylannarwgyrmgnakfvdemitdglwdafndyhmgitaeniaerwnisreeqdefal
asqkkaeeaiksgqfkdeivpvvikgrkgetvvdtdehprfgstieglaklkpafkkdgt
vtagnasglndcaavlvimsaekakelgvkplakivsygsagvdpaimgygpfyatkaai
ekagwtvdeldliesneafaaqslavakdlkfdmnkvnvnggaialghpigasgarilvt
lvhamqkrdakkglatlsigggqgtaillekc

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4n46B (B:)
mkevviasavrtaigsygkslkdvpavdlgataikeavkkagikpedvnevilgnvlqag
lgqnparqasfkaglpveipamtinkvcgsglrtvslaaqiikagdadviiaggmenmsr
apylannarwgyrmgnakfvdemitdglwdafndyhmgitaeniaerwnisreeqdefal
asqkkaeeaiksgqfkdeivpvvikgrkgetvvdtdehprfgstieglaklkpafkkdgt
vtagnasglndcaavlvimsaekakelgvkplakivsygsagvdpaimgygpfyatkaai
ekagwtvdeldliesneafaaqslavakdlkfdmnkvnvnggaialghpigasgarilvt
lvhamqkrdakkglatlsigggqgtaillekclehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4n46B (B:)
mkevviasavrtaigsygkslkdvpavdlgataikeavkkagikpedvnevilgnvlqag
lgqnparqasfkaglpveipamtinkvcgsglrtvslaaqiikagdadviiaggmenmsr
apylannarwgyrmgnakfvdemitdglwdafndyhmgitaeniaerwnisreeqdefal
asqkkaeeaiksgqfkdeivpvvikgrkgetvvdtdehprfgstieglaklkpafkkdgt
vtagnasglndcaavlvimsaekakelgvkplakivsygsagvdpaimgygpfyatkaai
ekagwtvdeldliesneafaaqslavakdlkfdmnkvnvnggaialghpigasgarilvt
lvhamqkrdakkglatlsigggqgtaillekc