PDB entry 4n37

View 4n37 on RCSB PDB site
Description: Structure of langerin CRD I313 D288 complexed with Me-Man
Class: sugar binding protein
Keywords: CRD carbohydrate complex, carbohydrate-recognition domain, C-type lectin on Langerhans cells, Carbohydrate/Sugar Binding, receptor on Langerhans cells, SUGAR BINDING PROTEIN
Deposited on 2013-10-06, released 2013-11-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: C-type lectin domain family 4 member K
    Species: Homo sapiens [TaxId:9606]
    Gene: CD207, CLEC4K
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UJ71
      • variant (85)
      • engineered mutation (95)
      • engineered mutation (120)
    Domains in SCOPe 2.07: d4n37a_
  • Chain 'B':
    Compound: C-type lectin domain family 4 member K
    Species: Homo sapiens [TaxId:9606]
    Gene: CD207, CLEC4K
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UJ71
      • variant (85)
      • engineered mutation (95)
      • engineered mutation (120)
    Domains in SCOPe 2.07: d4n37b_
  • Chain 'C':
    Compound: C-type lectin domain family 4 member K
    Species: Homo sapiens [TaxId:9606]
    Gene: CD207, CLEC4K
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UJ71
      • variant (85)
      • engineered mutation (95)
      • engineered mutation (120)
    Domains in SCOPe 2.07: d4n37c_
  • Chain 'D':
    Compound: C-type lectin domain family 4 member K
    Species: Homo sapiens [TaxId:9606]
    Gene: CD207, CLEC4K
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UJ71
      • variant (85)
      • engineered mutation (95)
      • engineered mutation (120)
    Domains in SCOPe 2.07: d4n37d_
  • Heterogens: MMA, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4n37A (A:)
    qvvsqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliyw
    igltkagmegdwswvddtpfnkvqsarfwipgepndagnnehcgnikapslqawndapcd
    itflfickrpyvpsep
    

    Sequence, based on observed residues (ATOM records): (download)
    >4n37A (A:)
    gwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliywigltk
    agmegdwswvddtpfnkvqsarfwipgepndagnnehcgnikapslqawndapcditflf
    ickrpyvp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4n37B (B:)
    qvvsqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliyw
    igltkagmegdwswvddtpfnkvqsarfwipgepndagnnehcgnikapslqawndapcd
    itflfickrpyvpsep
    

    Sequence, based on observed residues (ATOM records): (download)
    >4n37B (B:)
    gwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliywigltk
    agmegdwswvddtpfnkvqsarfwipgepndagnnehcgnikapslqawndapcditflf
    ickrpyvp
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4n37C (C:)
    qvvsqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliyw
    igltkagmegdwswvddtpfnkvqsarfwipgepndagnnehcgnikapslqawndapcd
    itflfickrpyvpsep
    

    Sequence, based on observed residues (ATOM records): (download)
    >4n37C (C:)
    sqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliywigl
    tkagmegdwswvddtpfnkvqsarfwipgepndagnnehcgnikapslqawndapcditf
    lfickrpyvp
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4n37D (D:)
    qvvsqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliyw
    igltkagmegdwswvddtpfnkvqsarfwipgepndagnnehcgnikapslqawndapcd
    itflfickrpyvpsep
    

    Sequence, based on observed residues (ATOM records): (download)
    >4n37D (D:)
    qgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliywiglt
    kagmegdwswvddtpfnkvqsarfwipgepndagnnehcgnikapslqawndapcditfl
    fickrpyv